2007 Red Cells Gordon Research Conference

2007 红细胞戈登研究会议

• 批准号: 7328473
• 负责人: JON S MORROW
• 金额: $ 1.75万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-18 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7328473
• 关键词: Affect; Area; Biogenesis; Cell Maturation; Cell Membrane Structures; Cellular biology; Characteristics; Clinical; Clinical Research; Collaborations; Cytoskeletal Proteins; Depth; Development; Diamond-Blackfan anemia; Discipline; Disease; Erythrocytes; Erythroid; Erythropoiesis; Event; Fanconi' s Anemia; Fostering; Gene Expression; Gene Expression Regulation; Hematopoiesis; Individual; Malaria; Membrane; Membrane Proteins; Play; Process; Proteins; Regulation; Regulator Genes; Research; Research Personnel; Role; Scientist; Signal Transduction; Stem cells; Translating; erythroid differentiation; interest; lectures; planetary Atmosphere; posters; symposium; transcription factor

DESCRIPTION (provided by applicant): The Red Cell Gordon Conference has provided an informal atmosphere for in-depth discussions on topics related to red cell biology, regulation of erythroid gene expression, hematopoiesis, and clinically related issues. The meeting, which is consistently oversubscribed, draws leading scientists and clinicians from around the world. The 2007 meeting should be especially noteworthy, given the major recent advances in several of the prominent areas. Nine individual sessions are planned. All will feature a short introductory lecture, followed by a topical keynote and four or five full lectures, and one or two shorter talks provided by trainees or junior investigators or late-breaking discoveries of major significance. A new component of this Gordon Conference will be an entire session devoted to a conferee-wide discussion of how the gene-regulatory events guiding erythroid stem-cell maturation are translated into the phenotypic transitions characteristic of this process. We anticipate that this will be a particularly timely and lively discussion that will draw on the broad expertise of all in attendance, from those studying gene regulation to those studying membrane structure and biogenesis. Other major topics include several clinical disorders, from malaria to rare but poorly understood and important diseases affecting the red cell, such as PNH, Diamond Blackfan anemia, and Fanconi's anemia. The session topics are: Session 1. Developmental aspects of hematopoiesis; Session 2. Membrane-cytoskeletal protein interactions; Session 3. Global regulation of gene expression; Session 4. Transcription factors; Session 5. Control of protein diversity during erythropoiesis; Session 6. Signaling in mature and developing red cells; Session 7. Phenotypic transition during erythroid differentiation Session 8. Red cell membrane structure and dynamics; Session 9. Red cell disorders. Afternoon poster sessions will feature a mix of presentations from all disciplines. The diversity of scientific approaches/interests combined with the richness of discussions of previous Red Cell Gordon Conferences has led to numerous productive collaborations and fostered new developments in basic and clinical research. It is also noteworthy that many of our most fundamental understandings of proteins, membranes, cell biology, and many diseases began with studies in the red cell. The Red Cell Gordon Conference has played a major role in fostering these advances. The 2007 conference will continue this tradition.

描述（由申请人提供）： 红细胞戈登会议为与红细胞生物学，红细胞生物学相关的主题，红细胞基因表达，造血和临床相关的问题提供了深入讨论提供了非正式的氛围。这次会议始终被超额认购，吸引了来自世界各地的主要科学家和临床医生。考虑到几个著名领域的最新进展，2007年的会议应该特别值得注意。计划了九次会议。所有这些都将进行简短的介绍性演讲，然后进行主题主题演讲和四到五个完整的讲座，以及受训者或初级调查人员或重大意义的后期发现的一两个较短的演讲。这次戈登会议的一个新组成部分将是整个会议，旨在详细讨论如何将基因调节事件指导指导红细胞干细胞成熟的基因调节事件转化为该过程的表型过渡的特征。我们预计，这将是一个特别及时，活泼的讨论，将借鉴所有参加人数的广泛专业知识，从研究基因调节的人到研究膜结构和生物发生的人。其他主要主题包括几种临床疾病，从疟疾到罕见但知之甚少，很重要 影响红细胞的疾病，例如PNH，钻石黑芬贫血和范科尼的贫血。会议主题是：会议1。造血的发展方面；第2节。膜 - 细胞骨架蛋白相互作用；第3节。基因表达的全球调节；第4节。转录因子；第5节。促红细胞生成期间蛋白质多样性的控制；第6节。成熟和发展红细胞中的信号传导；第7节。红细胞分化过程中的表型过渡 第8节。红细胞膜结构和动力学；第9节。红细胞疾病。下午的海报会议将包括来自所有学科的演讲。科学方法/兴趣的多样性结合了先前红细胞戈登会议的丰富性，导致了许多生产性合作，并促进了基础和临床研究方面的新发展。还值得注意的是，我们对蛋白质，膜，细胞生物学和许多疾病的许多最基本的理解始于红细胞中的研究。红细胞戈登会议在促进这些进步方面发挥了重要作用。 2007年会议将继续这一传统。