Training in the Genome Sciences and the Hemoglobinopathies

基因组科学和血红蛋白病培训

基本信息

批准号：
7228255
负责人：
Huntington F Willard
金额：
$ 12.6万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-05-01 至 2011-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7228255
关键词：
Academic Medical Centers Adult Appendix Applications Grants Appointment Area Arts Award Basic Science Behavior Bioinformatics Biology Board Certification Budgets Caliber Cardiovascular system Certification Characteristics Childhood Clinic Clinical Clinical Management Clinical Medicine Clinical Research Collaborations Commit Committee Members Communities Competence Computational Biology Congenital Anemia Core Facility Critiques DNA Microarray Chip DNA Microarray format Data Data Analyses Data Set Decision Making Depth Development Discipline Disease Doctor of Philosophy Educational Curriculum Educational workshop Effectiveness Elements Enrollment Ensure Environment Epigenetic Process Equilibrium Equipment Evaluation Event Exposure to Faculty Fellowship Fellowship Program Fetal Hemoglobin Fostering Foundations Functional disorder Funding Funding Agency Future Gene Expression Genetic Genome Genomics Genotype Goals Grant Grant Review Process Hand Health Hearing Hematology Hematopoiesis Hemoglobin Hemoglobinopathies Hemostatic function Human Genetics Huntington Disease Indium Individual Institutes Institution Instruction Internal Medicine International Internet Internist Investigation Journals Knowledge Laboratories Learning Left Literature Malignant - descriptor Master&apos s Degree Medical Medical Genetics Medicine Mentors Methods Microarray Analysis Modeling Molecular Molecular Biology Techniques Molecular Medicine Monitor Nature North Carolina Numbers One-Step dentin bonding system Outcomes Research Pain Paper Participant Patients Pediatrics Performance Physicians Physiology Policies Population Study Positioning Attribute Postdoctoral Fellow Prevention Principal Investigator Process Productivity Program Evaluation Proteomics Protocols documentation Purpose Range Reaction Reading Recording of previous events Request for Proposals Research Research Activity Research Design Research Ethics Committees Research Personnel Research Project Grants Research Subjects Research Training Resources Risk Rotation Sampling Sampling Studies San Francisco Science Science Policy Scientist Series Serum Sickle Cell Sickle Cell Anemia Site Social Policies South Carolina Staging Standards of Weights and Measures Students Suggestion System Tanzania Technology Thailand Thalassemia Therapeutic Thinking Thrombosis Time Training Training Programs Training Support Training and Education Transfusion United States National Institutes of Health Universities Update Vascular Diseases Virginia Visit Week Work Writing base career cell growth cellular oncology clinical conference cohort day design desire experience falls follow-up forest forging immunohematology improved instrument interest knowledge base lectures mass spectrometer medical schools medical specialties member multidisciplinary new technology oncology pediatrician post-doctoral training practical application prognostic programs research and development research study sickling skills social success symposium therapy outcome tool

项目摘要

DESCRIPTION (provided by applicant): The overall goal of the Duke University - University of North Carolina at Chapel Hill (UNC) Training Program in the Genome Sciences and the Hemoglobinopathies is to train a cohort of both domestic and foreign postdoctoral fellows to be outstanding investigators of the basis for and treatment of the hemoglobinopathies, using genomics and related large-scale and high-throughput approaches in the genome sciences. Whether each trainee's chosen area of focus is in genomics, proteomics or computational biology and whether one's future research is basic, translational or clinical, each fellow will be expected to gain a broad and comprehensive understanding of the genome sciences as applied to ongoing research projects in the hemoglobinopathies. Training towards this goal will be achieved through: advanced coursework; extensive rotations in genomics, proteomics, and computational laboratories; a weekly colloquium involving researchers in the genome sciences; research in laboratories with active programs in hemoglobinopathy research; and co-mentoring by training faculty with expertise both in the genome sciences and in the hemoglobinopathies in order to develop a full appreciation for the multidisciplinary nature of this training program. The training program will be directed jointly by the Director of the Duke Institute for Genome Sciences & Policy and by the Director of the Duke-UNC Comprehensive Sickle Cell Center. Outstanding fellows will be identified from among a strong pool of applicants to existing postdoctoral training opportunities at both Duke and UNC in hematology, transfusion medicine, medical genomics, vascular disease and the genome sciences; from applicants to individual mentors at Duke and UNC; and from applicants identified by an international advisory group consisting of colleagues and collaborators in Tanzania and Thailand. Research opportunities will be provided by a group of more than 25 Duke and UNC faculty members with expertise in the genome sciences and in the hemoglobinopathies. We will develop a group of domestic and foreign colleagues who are dedicated to advance our understanding and treatment of the hemoglobinopathies. This network of investigators will form the basis for an ongoing series of international collaborations to reduce the pain and burden of these disorders.

描述（由申请人提供）：杜克大学 - 北卡罗来纳大学教堂山（UNC）培训计划的总体目标和血红蛋白疗法是培训家庭和外国博士后研究员的同龄人，以使用基因组和相关的大型研究和高度治疗基因组和高质量的杰出研究者。每个学员选择的重点领域是基因组学，蛋白质组学还是计算生物学，以及未来的研究是基本的研究，转化还是临床，每个人都将获得对基因组科学的广泛而全面的了解，以适用于血红蛋白病的正在进行的研究项目。将通过以下方式实现这一目标的培训：高级课程；基因组学，蛋白质组学和计算实验室的广泛旋转；每周涉及研究人员参与基因组科学的座谈会；通过血红蛋白疗法研究的活跃计划的实验室研究；并通过培训教师在基因组科学和血红蛋白病中的专业知识，以对该培训计划的多学科性质产生全面的欣赏。该培训计划将由杜克大学基因组科学与政策研究所主任以及Duke-Unc综合镰状细胞中心的主任共同指挥。从强大的申请人中，将在血液学，输血医学，医学基因组学，血管疾病和基因组科学的杜克大学和UNC的现有博士后培训机会中确定出色的研究员；从申请人到杜克大学和UNC的个人导师；来自由国际咨询小组确定的申请人，该小组由坦桑尼亚和泰国的同事和合作者组成。一组超过25名公爵和UNC教职员工将提供研究机会，这些教师在基因组科学和血红蛋白疗法方面具有专业知识。我们将开发一群家庭和外国同事，他们致力于提高我们对血红蛋白病的理解和治疗。这个调查人员网络将构成一系列国际合作的基础，以减轻这些疾病的痛苦和负担。