Portable EEG Recorder for Household Surveys

用于家庭调查的便携式脑电图记录仪

• 批准号: 7172053
• 负责人: DANIEL S HEDIN
• 金额: $ 10万
• 依托单位: ADVANCED MEDICAL ELECTRONICS CORPORATION
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7172053
• 关键词: Age; Aging; Alzheimer' s Disease; Amplifiers; Anatomy; Apple; Brain; Brain Diseases; Businesses; Characteristics; Clinical; Computer Simulation; Computer software; Computers; Country; Daily; Data; Data Quality; Dementia; Deterioration; Development Plans; Devices; Diagnostic; Elderly; Electrodes; Electroencephalogram; Electronics; Ensure; Epilepsy; Equipment; Explosion; Future; Goals; Grant; Home environment; Hour; Household; Left; Letters; Literature; Lithium; Longitudinal Studies; Longitudinal Surveys; Magnetic Resonance Imaging; Manufacturer Name; Marketing; Mechanics; Medical; Medical Electronics; Memory; Modeling; Monitor; Music; Patients; Persons; Phase; Poaceae; Positron-Emission Tomography; Postage Stamps; Price; Principal Investigator; Production; Provider; Reporting; Research; Research Personnel; Resources; Rhode Island; Sales; Scalp structure; Scheme; Small Business Funding Mechanisms; Small Business Innovation Research Grant; Surveys; Symptoms; System; Technology; Testing; Time; Training; Twin Multiple Birth; United States Food and Drug Administration; United States National Institutes of Health; Weight; Work; age related; base; commercial application; commercialization; cost; density; design; digital; experience; innovation; instrument; interest; patient monitoring device; programs; prototype; size; tool

DESCRIPTION (provided by applicant): Advanced Medical Electronics Corporation (AME) proposes to develop a miniature portable electroencephalograph (EEG) recorder that can be easily used in the home to collect data for longitudinal surveys of the elderly. The device will be capable of using new dry electrode technology that promises to greatly simplify the attachment of EEG scalp electrodes. Dry electrode technology will allow a minimally trained person to make the attachment to a patient and collect a 30 minute segment of data. In phase I, AME will identify the most promising dry electrode technology to integrate with the recorder in phase II. The proposed pocket size EEG recorder will be small enough to be worn relatively unobtrusive during daily activities. This will allow the device to be used in ambulatory epilepsy monitoring applications and will create a larger market for the portable EEG recorder. Researchers conducting longitudinal EEG surveys will benefit by sharing a market with ambulatory epilepsy monitoring because of reduced production costs. Alzheimer's disease (AD) is an age-related and irreversible brain disorder that develops over a period of years. AD symptoms typically first appear after age 65 and are the subject of longitudinal studies. There has been recent interest in the use of the electroencephalogram (EEG) to screen patients and identify the first signs of AD. There is extensive literature that reports changes in quantitative electroencephalogram (QEEG) with aging and a relationship between magnitude of changes and degree of clinical deterioration in progressive dementia. The use of EEG provides a low cost alternative to more sophisticated tools like MRI and PET to distinguish characteristics of brain function and anatomy that indicate future problems. The proposed miniature portable EEG recorder with easily applied dry electrode technology can be applied in the home to collect data for longitudinal surveys of the elderly.

描述（由申请人提供）：先进医疗电子公司（AME）提议开发一种微型便携式脑电图（EEG）记录仪，可以方便地在家中使用，收集老年人纵向调查的数据。该设备将能够使用新的干电极技术，有望大大简化脑电图头皮电极的连接。干电极技术将允许经过最低限度培训的人员将其连接到患者身上并收集 30 分钟的数据片段。在第一阶段，AME 将确定最有前途的干电极技术，以便与第二阶段的记录仪集成。所提议的袖珍脑电图记录仪将足够小，以便在日常活动中相对不引人注目地佩戴。这将使该设备能够用于动态癫痫监测应用，并将为便携式脑电图记录仪创造更大的市场。由于生产成本降低，进行纵向脑电图调查的研究人员将受益于与动态癫痫监测共享市场。阿尔茨海默氏病 (AD) 是一种与年龄相关且不可逆转的脑部疾病，需要经过数年的时间才能形成。 AD 症状通常在 65 岁之后首次出现，并且是纵向研究的主题。最近人们对使用脑电图（EEG）来筛查患者并识别 AD 的最初迹象产生了兴趣。有大量文献报道了定量脑电图（QEEG）随年龄的变化以及变化幅度与进行性痴呆临床恶化程度之间的关系。脑电图的使用为 MRI 和 PET 等更复杂的工具提供了一种低成本的替代方案，可以区分表明未来问题的大脑功能和解剖特征。所提出的微型便携式脑电图记录仪具有易于应用的干电极技术，可以在家中应用来收集老年人纵向调查的数据。