Device for pneumothorax diagnosis using breath sounds

利用呼吸音诊断气胸的装置

基本信息

批准号：
6930402
负责人：
HANSEN A MANSY
金额：
$ 58.41万
依托单位：
RUSH UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-08-01 至 2008-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6930402
关键词：
bioengineering /biomedical engineering biomedical equipment development biosensor device clinical research computer assisted diagnosis computer simulation diagnosis design /evaluation dogs human subject monitoring device noninvasive diagnosis pneumothorax disorder portable biomedical equipment pulmonary respiration radiography respiratory disorder diagnosis sound

项目摘要

DESCRIPTION (provided by applicant): The primary focus of the current application is to develop a new device for PTX detection using computerized analysis of breath sounds. Pilot animal studies suggested that this approach may have high diagnostic power. The proposed human, animal, and mechanical experiments will utilize acoustic measurements and analyses that are designed to test feasibility, optimize the technique, and study audible-frequency acoustic wave behavior in the pulmonary system. Devices resulting from this technology are expected to be accurate, easy-to-use, radiation-free, inexpensive, rapid, portable, and safe. The long-term objective of this project is to develop techniques for the diagnosis of medical conditions using computer-assisted auscultation of body sounds. While the use of stethoscopes for medical diagnosis is common, this approach is skill dependent, can only provide qualitative information, and may suffer from inherent limitations of human ability to discern certain acoustic differences. The innovative nature of the proposed work is the implementation of simultaneous multi-sensor acquisition of body sounds combined with state of the art digital processing algorithms. The accumulated knowledge base and experience from the proposed work may be useful in developing a broad range of diagnostic technologies including cardiovascular, gastrointestinal, muscle, and joint applications. For example, earlier studies have suggested potential utility for diagnosis of such conditions as small bowel obstruction, pneumoperitoneum, vascular access compromise, coronary occlusions, and osteoporosis.

描述（由申请人提供）：当前应用的主要重点是开发一种使用呼吸音计算机分析进行 PTX 检测的新设备。试点动物研究表明这种方法可能具有很高的诊断能力。拟议的人体、动物和机械实验将利用声学测量和分析，旨在测试可行性、优化技术并研究肺部系统中的可听频率声波行为。由该技术产生的设备预计将是准确的、易于使用的、无辐射的、廉价的、快速的、便携的和安全的。该项目的长期目标是开发利用计算机辅助听诊身体声音来诊断医疗状况的技术。虽然使用听诊器进行医学诊断很常见，但这种方法依赖于技能，只能提供定性信息，并且可能受到人类辨别某些声音差异的能力的固有限制。所提出的工作的创新本质是实现身体声音的同时多传感器采集与最先进的数字处理算法相结合。拟议工作中积累的知识库和经验可能有助于开发广泛的诊断技术，包括心血管、胃肠道、肌肉和关节应用。例如，早期研究表明其对于诊断小肠梗阻、气腹、血管通路受损、冠状动脉闭塞和骨质疏松症等疾病具有潜在的实用性。