Psychoeducation for HCV and Alcohol Behaviors

HCV 和酒精行为的心理教育

• 批准号: 7294926
• 负责人: CAROL S NORTH
• 金额: $ 58.75万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7294926
• 关键词: Adherence; Adverse effects; Behavior; Caring; Chronic Disease; Control Groups; Daily; Disease; Drug usage; Education; Educational Curriculum; Educational Intervention; Effectiveness of Interventions; Eligibility Determination; Event; Family; Family Characteristics; Family member; Goals; Health Professional; Hepatitis C; Hepatitis C virus; Housing; Individual; Insurance; Interest Group; Interferons; Intervention; Knowledge; Life; Longevity; Measures; Mediating; Medical; Mental Health; Mental disorders; Modeling; Morbidity - disease rate; Motivation; Outcome; Outcome Measure; Participant; Patients; Pattern; Personality; Pharmaceutical Preparations; Population; Problem Solving; Procedures; Process; Provider; Psychiatric therapeutic procedure; Psychopathology; Quality of life; Randomized Controlled Trials; Readiness; Recommendation; Research Project Grants; Ribavirin; Risk-Taking; Services; Social Functioning; Social support; Solutions; Special Equipment; Standards of Weights and Measures; Substance Abuse, Other; Symptoms; Testing; Training; Translating; Transportation; Treatment Protocols; Viral Load result; alcohol and other drug; alcohol behavior; base; burden of illness; compliance behavior; coping; cost; depressive symptoms; experience; improved; innovation; member; mortality; programs; psychoeducation; satisfaction; severe mental illness; skills; Adherence; Adverse effects; Behavior; Caring; Chronic Disease; Control Groups; Daily; Disease; Drug usage; Education; Educational Curriculum; Educational Intervention; Effectiveness of Interventions; Eligibility Determination; Event; Family; Family Characteristics; Family member; Goals; Health Professional; Hepatitis C; Hepatitis C virus; Housing; Individual; Insurance; Interest Group; Interferons; Intervention; Knowledge; Life; Longevity; Measures; Mediating; Medical; Mental Health; Mental disorders; Modeling; Morbidity - disease rate; Motivation; Outcome; Outcome Measure; Participant; Patients; Pattern; Personality; Pharmaceutical Preparations; Population; Problem Solving; Procedures; Process; Provider; Psychiatric therapeutic procedure; Psychopathology; Quality of life; Randomized Controlled Trials; Readiness; Recommendation; Research Project Grants; Ribavirin; Risk-Taking; Services; Social Functioning; Social support; Solutions; Special Equipment; Standards of Weights and Measures; Substance Abuse, Other; Symptoms; Testing; Training; Translating; Transportation; Treatment Protocols; Viral Load result; alcohol and other drug; alcohol behavior; base; burden of illness; compliance behavior; coping; cost; depressive symptoms; experience; improved; innovation; member; mortality; programs; psychoeducation; satisfaction; severe mental illness; skills

DESCRIPTION (provided by applicant): Medical treatment of hepatitis C (HCV) requires steadfast adherence to be effective, yet physical and psychiatric side effects induced by current medications (interferon and ribavirin) undermine patient motivation and consistency. Barriers to this population's access to vital services, including transportation and insurance and lack of stable housing, pose further threats to optimal management of HCV. Promotion of adherence and patient support may be enhanced if family members and significant others can be enlisted to join HCV providers in this effort. Psychoeducation programs, demonstrated by this team to be effective for patients and families coping with serious mental illness, can have direct relevance and application to HCV. The proposed project will apply a unique, effective family-responsive psychoeducation program (PERF) for HCV, which has not been previously attempted in this population. HCV-PERF will be compared with a didactic education intervention in a randomized controlled trial with 400 HCV patients. The goal is to demonstrate that the intervention will enlarge the eligibility of some patients for HCV treatment and help sustain others through it. The program will provide HCV education and a forum to discuss problems in daily living and coping with the illness in a supportive, proactive, and problem-focused agenda. The topics and issues covered in the psychoeducation groups will emerge from expressed interests of the group members, generating participant-specific discussions emphasizing and reinforcing personalized solutions to the problems of living with a chronic illness and its difficult treatment regimen. This intervention will build on the skills of HCV and mental health professionals with two professionals, one with HCV treatment expertise and the other a with a mental health background, leading the psychoeducation groups. Study participants will be evaluated with several psychospacial/psychiatric measures including coping, functioning, social support, and quality of life as they contemplate or receive standard medical care for HCV. (This research project will not interfere with usual HCV treatment regimens. The problem-solving oriented psychoeducation program is not a replacement for psychiatric care, and psychiatric referrals will be facilitated when appropriate.) Effectiveness of the intervention will be measured through multiple outcome measures, including medical markers such as viral load. This innovative intervention is inexpensive, requires no special equipment or difficult procedures, and can be exported to diverse HCV treatment settings and implemented without extensive training. HCV-PERF has the potential for major positive impact on the HCV population to save lives, reduce costs, and improve medical outcomes.

描述（由申请人提供）：丙型肝炎（HCV）的医学治疗要求坚定的依从性是有效的，但由于当前药物（Interferon和Ibavirin）引起的身体和精神副作用会破坏患者的动机和一致性。该人群获得重要服务的障碍，包括运输和保险以及缺乏稳定的住房，对HCV的最佳管理构成了进一步的威胁。如果可以邀请家庭成员和重要的其他人加入HCV提供者，则可以提高依从性和患者支持。该团队证明的心理教育计划对应对严重精神疾病的患者和家庭有效，可以直接相关性并适用于HCV。拟议的项目将针对HCV应用独特的，有效的家庭响应性心理教育计划（PERF），该计划以前尚未尝试过该人群。 HCV-PERF将与400名HCV患者的随机对照试验中的教学教育干预进行比较。目的是证明干预措施将扩大某些患者进行HCV治疗的资格，并通过它帮助维持其他患者的资格。该计划将提供HCV教育和论坛，讨论日常生活中的问题，并以支持性，积极主动和以问题为中心的议程来应对疾病。心理教育小组所涵盖的主题和问题将来自小组成员的明确利益，引起特定于参与者的讨论，强调并加强了个性化解决方案，以解决患有慢性疾病及其困难治疗方案的问题。这种干预将基于HCV和精神卫生专业人员的技能，其中一名具有HCV治疗专业知识，另一个具有心理健康背景，领导了心理教育组。研究参与者将通过几种精神群体/精神病学措施进行评估，包括应对，功能，社会支持和生活质量，因为他们考虑或接受HCV的标准医疗服务。 （该研究项目不会干扰通常的HCV治疗方案。解决问题的精神教育计划并不能替代精神病护理，并且在适当的情况下将促进精神病学转诊。这种创新的干预措施价格便宜，不需要特殊的设备或困难程序，并且可以出口到不同的HCV治疗环境，并在没有广泛培训的情况下实施。 HCV-PERF有可能对HCV人群产生重大积极影响，以挽救生命，降低成本并改善医疗结果。