Physical Equipment Facilities

物理设备设施

• 批准号: 7140013
• 负责人: Christopher James MCKNIGHT
• 金额: $ 18.91万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7140013
• 关键词: X ray crystallography; biomedical equipment resource; biomedical facility; blood lipoprotein; calorimetry; cardiovascular disorder; circular dichroism; electron microscopy; molecular dynamics; nuclear magnetic resonance spectroscopy; protein structure function; structural biology

The function of this core unit is to centralize the facilities and expertise of the major physical chemical and structural techniques utilized in the four project areas forming the Program Project. Facilities Provided by the Core Unit: 1) X-Ray Crystallography 2) Nuclear Magnetic Resonance Spectroscopy Nuclei: 13C, 1H, 2H, 31P, 15N and all other NMR nuclei 3) Calorimetry High sensitivity adiabatic differential scanning, titration 4) Electron Microscopy Negative staining, sectioning and morphological analysis 5) Structural Electron Microscopy and Image Processing 6) Protein Crystallization 7) Circular Dichroism Spectroscopy Near and far UV 8) Molecular Modeling, Graphics, and Molecular Dynamics 9) Crystallographic Computing 10) Surface Monolayer Techniques

该核心单位的功能是集中主要物理化学的设施和专业知识 以及构成该计划项目的四个项目领域中使用的结构技术。 核心单位提供的设施： 1) X射线晶体学 2) 核磁共振波谱分析 原子核：13C、1H、2H、31P、15N 和所有其他 NMR 原子核 3) 量热法 高灵敏度绝热差示扫描、滴定 4) 电子显微镜 负染色、切片和形态分析 5) 结构电子显微镜和图像处理 6) 蛋白质结晶 7) 圆二色光谱 近紫外线和远紫外线 8) 分子建模、图形和分子动力学 9) 晶体学计算 10) 表面单层技术