Age-27 Follow-up of Early Preventive Intervention

27 岁早期预防干预的后续行动

基本信息

批准号：
7254690
负责人：
DAVID L OLDS
金额：
$ 47.64万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-09-28 至 2009-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7254690
关键词：
Adult Age Age-Years Alcohol consumption Behavior Behavioral Birth Birth Intervals Child Child Abuse and Neglect Child Welfare Communication Condition Control Groups Early Intervention Economics Education Effectiveness of Interventions Environmental Risk Factor Expenditure Generations Genes Genetic Genetic Polymorphism Genetic Predisposition to Disease Government Growth Home environment Home visitation House Call Imprisonment Individual Interpersonal Violence Life Cycle Stages Literature Long-Term Effects Low income Marriage Mental Health Methaqualone Military Personnel Mothers New York Nicotine Nurses Occupations Phase Pregnancy Preventive Intervention Productivity Randomized Controlled Trials Rate Receptor Gene Research Risk Running Sampling Social Welfare Substance abuse problem Taxes Tobacco use Training Unmarried Unmarried Mother Violence Visit Visiting Nurse Woman Work Youth assault career comparison group criminal behavior design dopamine transporter employment/unemployment experience fetal tobacco exposure follow-up infancy men prenatal prenatal health programs relationship violence young adult

项目摘要

This study is a longitudinal follow-up of 340 young men and women who have participated in a randomized controlled trial of prenatal and infancy home visiting by nurses in Elmira, New York since their mothers registered in the trial during their pregnancies between 1977 and 1980. The study will be conducted when these first-born children turn 27 years of age. It is designed to determine whether highly promising effects found for nurse home visiting with this sample when these young adults were 15 years of age endure through age 27. Specifically, the current proposal is designed to determine, 25 years after the Elmira program ended at child age 2, whether: 1) nurse-visited young adult offspring differ from comparison-group young adults in: a) their economic productivity (e.g., unemployment, employment in jobs with limited opportunities for career growth, use of welfare; rates of out-of wedlock births); b) the quality of their partnered relationships (rates of interpersonal violence, commitment, and quality of communication); c) their rates of child abuse and neglect perpetrated on their own children; d) their rates of criminal behavior, arrests, convictions, and imprisonment; and e) their mental health and abuse of substances: 2) the effects of the program on the young adults' economic productivity are concentrated on those individuals born to mothers who were low-income and unmarried at registration during their pregnancies; 3) the effects of the program on adult criminality, violent behavior, and second-generation child abuse and neglect, in prcliminary studies, are concentrated on those individuals with genetic vulnerabilities for behavioral dysregulation (functional polymorphisms in the gene that encodes MAOA, the dopamine transporter gene, and the (7 nicotine receptor gene) in combination with environmental risks (prenatal tobacco exposure and child maltreatment); 4) the effect of the program on young adults' adaptive functioning is explained by the combined effects of the program on their mothers" prenatal health-related behaviors, life-course (rates of marriage, subsequent children, and welfare use), and their experience of child abuse and neglect; and 5) nurse-visited young adults produced fewer government expenditures and higher tax revenues compared to young adults assigned to the comparison condition. This study adds to the literature on the long-term effects of early intervention and marks a new phase in this program of research by examining, in preliminary studies, the extent to which the effects of the intervention are concentrated in individuals who are at dual risk for adult criminality because of combined genetic and environmental risks.

这项研究是对340名年轻男女进行的纵向随访，他们参加了纽约州埃尔米拉（Elmira）的护士访问产前和婴儿期的随机对照试验，因为他们的母亲在1977年至1980年之间的怀孕期间在审判中注册了。这项研究将在这些第一个年龄段27岁的孩子年龄27岁时进行。它旨在确定在这些年轻人年龄15岁至27岁的年轻人持续27岁时，是否会发现护士回家的高度有希望的效果。特别是，当前的建议旨在确定Elmira计划在Elmira计划以2年结束的25年结束后25年，是否：1）是否以下是：1）护士与年轻人的成年人的成年人在以下情况下不同：E. a）在以下方面的成年人（E. A）的生产率：E。E. A），E。E. a。使用福利； b）他们合作关系的质量（人际暴力，承诺和沟通质量的速度）； c）他们的虐待和忽视儿童率是在自己的孩子身上进行的； d）他们的犯罪行为率，逮捕，定罪和监禁； e）他们的心理健康和物质滥用：2）该计划对年轻人经济生产力的影响集中在那些低收入和低收入母亲的人身上怀孕期间未婚； 3）在预先研究中，该计划对成人犯罪，暴力行为以及第二代儿童虐待和忽视的影响集中在那些具有行为失调遗传脆弱性的个体上儿童虐待）； 4）该计划对年轻人的适应性功能的影响是由该计划对母亲的综合作用来解释的，“产前健康相关的行为，生命过程，婚姻，随后的儿童和福利率）以及他们对儿童虐待和忽视的经历；与分配给比较条件的年轻人相比，年轻人产生的政府支出和税收更高。这项研究增加了有关早期干预措施的长期影响的文献，并通过检查初步研究，在该研究计划中标志着新阶段的新阶段，由于遗传和环境风险的综合，干预措施集中在对成人犯罪双重风险的个人中。