TEMPERATURE AND SAR CALCULATIONS FOR A HUMAN HEAD WITHIN VOLUME AND SURFACE COI

人体头部在体积和表面 COI 内的温度和 SAR 计算

• 批准号: 7181952
• 负责人: Christopher M Collins
• 金额: $ 4.98万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-01 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7181952
• 关键词: bioimaging /biomedical imaging; biomedical equipment resource; biomedical resource; clinical research; human subject; magnetic resonance imaging; method development; nuclear magnetic resonance spectroscopy

DESCRIPTION (provided by applicant): Center for Magnetic Resonance Research at the University of Minnesota is an interdepartmental and interdisciplinary research laboratory that has been funded as a Biotechnology Research Resource (BTRR) during the last nine years. The central research focus of this BTRR is development and improvement of methodologies and technologies for high magnetic resonance (MR) imaging and spectroscopy, and providing state-of-the-art instrumentation, expertise and infrastructure to enable the faculty, trainees and staff of several institutions in the USA and abroad to carry out basic and applied biomedical research that utilizes these unique high magnetic field (4 to 9.4 Tesla) capabilities. The general aim of this application is to seek continued support for this Biomedical Technology Research Resource so as to pursue new methodological and technical developments and maintain a National Research Resource with unique instrumentation and expertise that is not readily available elsewhere. A central and primary aim of the Core projects is to develop techniques for obtaining simultaneous information on aspects of organ function, perfusion, oxygen extraction, metabolism, and anatomy in humans non-invasively, using the unique advantages provided by high magnetic fields, such as the high signal-to-noise ratio, increased susceptibility effects associated with blood for imaging brain function, longer Tls for measurement of tissue perfusion, increased chemical-shift resolution for improved detection of neurochemicals, and the use of magnetic isotopes of biologically active atoms, such as O-17, which are not accessible easily at low magnetic fields due to their low gyromagnetic ratio. These techniques have been and will continue to be utilized to support a large community of NIH funded researchers working in neurosciences, functional brain mapping, brain metabolism, metabolic disorders, and cardiac pathology and bioenergetics.

描述（由申请人提供）： 明尼苏达大学的磁共振研究中心是部门间和跨学科研究实验室，在过去的九年中已被资助为生物技术研究资源（BTRR）。 The central research focus of this BTRR is development and improvement of methodologies and technologies for high magnetic resonance (MR) imaging and spectroscopy, and providing state-of-the-art instrumentation, expertise and infrastructure to enable the faculty, trainees and staff of several institutions in the USA and abroad to carry out basic and applied biomedical research that utilizes these unique high magnetic field (4 to 9.4 Tesla) capabilities.该应用程序的总体目的是寻求对这项生物医学技术研究资源的持续支持，以追求新的方法论和技术发展，并维护具有独特的仪器和专业知识的国家研究资源，而其他地方不容易获得。 A central and primary aim of the Core projects is to develop techniques for obtaining simultaneous information on aspects of organ function, perfusion, oxygen extraction, metabolism, and anatomy in humans non-invasively, using the unique advantages provided by high magnetic fields, such as the high signal-to-noise ratio, increased susceptibility effects associated with blood for imaging brain function, longer Tls for measurement of tissue perfusion, increased chemical-shift resolution for改善了神经化学物质的检测，以及使用生物活性原子（例如O-17）的磁同位素的使用，由于其低旋转磁比，在低磁场上无法轻松访问它们。这些技术已经并且将继续被用来支持从事神经科学，功能性脑图，脑代谢，代谢障碍以及心脏病理学和生物能源学的大型NIH资助的研究人员。