Phase I/II Partnership in Biomedical Discovery

生物医学发现 I/II 期合作伙伴关系

• 批准号: 7204233
• 负责人: LEWIS A JACOBSON
• 金额: $ 25.84万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7204233
• 关键词: Address; Adoption; Age; Animal Model; Area; Attention; Attitude; Bacteria; Biological; Biological Models; Biological Sciences; Biology; Caenorhabditis elegans; Class; Country; Development; Education; Educational Curriculum; Educational process of instructing; Educational workshop; Environment; Evaluation; Faculty; Genetic; Genetic Screening; Goals; Hand; Health; Human; Institution; Instruction; Knowledge; Leadership; Learning; Mathematics; Methods; Modeling; Mutation; Nematoda; Participant; Pennsylvania; Phase; Play; Process; Research; Research Personnel; Research Project Grants; Role; Schools; Science; Secondary Schools; Secondary to; Series; Standards of Weights and Measures; Students; System; Techniques; Testing; Training; Translating; United States; Universities; Urination; Week; Yeasts; base; career; compare effectiveness; experience; high school; interest; lectures; novel; novel strategies; programs; research study; science education; skills; teacher; tool

DESCRIPTION (provided by applicant): The overall objective of this phase I/II project is to develop a model of how the scientific expertise of a research university can directly impact local K-12 science education, by introducing high school teachers and students to the inquiry-based process that is scientific research. Our fundamental premises are that true science knowledge requires active engagement in scientific inquiry, and that teachers and students so engaged can become agents of change in science education. To this end, we propose to immerse selected biology teachers and high school students in an 8-week summer Research Experience, during which they participate directly in cutting-edge research in a University environment. With the participation and guidance of nine University research labs, teacher-student teams in a single lab facility will perform genetic screens for new mutations using three sets of model organisms: bacteria, yeast and C. elegans. Although these research labs have diverse objectives and employ varied experimental approaches and different techniques, there is a common thread in that they use the methods and paradigms of genetics to study health-related problems of interest and concern to the public. Weekly Curriculum Roundtable meetings among participating teachers, a Teacher Advisory Board and University faculty will focus on developing inquiry-based education modules and experiment kits, based on these model organisms, for use in high school and middle-school classrooms, and on methods and mechanisms for assessing the impact of such modules. The modules will be tested, refined and disseminated in one-week Curricular Workshops for high school teachers (who have not done the Research Experience) in project years 2-5. During succeeding years, we will provide experiment Kits for high school classes, with which teachers who have been through our programs can implement the inquiry-based curricular modules. Project evaluations aim to compare teachers who have done the 8-week Research Experience with those who have done the one-week Curricular Workshop, with respect to adoption and effective use of the inquiry-based methods and modules, to track educational and career paths of student participants, and to assess the impact on learning in high school biology.

描述（由申请人提供）： I/II阶段项目的总体目标是开发一个模型，该模型通过向高中教师和学生介绍基于询问的过程，即科学研究，如何直接影响研究大学的科学专业知识直接影响本地K-12科学教育。我们的基本前提是，真正的科学知识需要积极参与科学探究，而如此敬业的教师和学生可以成为科学教育变化的代理。为此，我们建议将精选的生物学教师和高中生浸入8周的夏季研究经验中，在此期间他们直接参加了大学环境中的尖端研究。借助九个大学研究实验室的参与和指导，在单个实验室设施中，教师学生团队将使用三组模型生物进行新突变的基因筛选：细菌，酵母和秀丽隐杆线虫。尽管这些研究实验室具有多种目标，并采用了各种实验方法和不同的技术，但有一个共同点，因为它们使用遗传学的方法和范式来研究与健康相关的问题和对公众关注的问题。参加教师，教师顾问委员会和大学教师之间的每周课程圆桌会议将专注于基于这些模型生物的基于询问的教育模块和实验套件，用于在高中和中学教室中使用，以及用于评估此类模型影响的方法和机制。这些模块将在项目2-5年度的高中教师的一周课程研讨会上进行测试，完善和传播。在随后的几年中，我们将为高中课程提供实验套件，通过我们的计划的老师可以实施基于询问的课程模块。项目评估旨在比较那些已经进行了为期8周的研究经验的教师与那些在采用和有效利用基于询问的方法和模块的人方面进行了为期一周的课程研讨会的人，以跟踪学生参与者的教育和职业道路，并评估对高中生物学学习的影响。