COBRE: UVM: CORE D: TRANSLATIONAL NEUROSCIENCE TRAINING

COBRE：UVM：核心 D：转化神经科学培训

• 批准号: 7170478
• 负责人: FELIX P ECKENSTEIN
• 金额: $ 16.7万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7170478
• 关键词: biological signal transduction; neurogenetics; neuroregulation; neurosciences

DESCRIPTION (provided by applicant): The goal of this application is to establish a Center of Biomedical Research Excellence (COBRE) in Neuroscience at the University of Vermont (UVM). The specific aims of this proposal are: Specific Aim 1: Establish the research and intellectual infrastructure to support a University-wide Center for Neuroscience Excellence at UVM. Goals of this aim include: 1) to establish a mentoring program to support junior neuroscience faculty; 2) to establish an imaging/physiology core to support the research projects of the junior faculty; 3) to establish a cellular/molecular core to support the research projects of the junior faculty; 4) to establish a University-wide Neuroscience Seminar Series and Annual Neuroscience Retreat; 5) to establish a mechanism of communication between basic scientists and clinicians that facilitates development of translational research and 6) to establish a University-wide mechanism for Neuroscience Graduate Education. Specific Aim 2: Support the research development of a core group of junior faculty who will be future leaders in the Center for Neuroscience Excellence. Faculty to be supported and their project titles are: 1) Dr. Rona Delay, Department of Biology: Chloride homeostasis in olfactory neurons; 2) Dr. William Falls, Department of Psychology:Molecular and genetic analysis of learned fear reduction in mice; 3) Dr. Anthony Morielli, Department of Pharmacology: Kinase and cytoskeletal regulation of potassium channels; 4) Dr. Matthew Rand, Department of Anatomy and Neurobiology: Proteolytic modulation of Notch signaling in neurogenesis and 5) Dr. George Wellman, Department of Pharmacology: Mechanisms of cerebral vasospasm in subarachnoid hemorrhage. UVM has established investigators in three areas of neuroscience: molecular/developmental, cellular/systems and clinical/behavioral neuroscience. Award of this application would provide a mechanism to significantly expand research strength in these existing areas of neuroscience emphasis, to integrate basic with clinical neuroscience, and to promote research collaborations university-wide. A level of excellence in research and training will be fostered that is not possible without external support. Productivity of both junior and senior investigators will be stimulated, and a long term mentoring framework will be created. UVM is a small institution in a rural state with limited resources; an award would substantially expand our research infrastructure and significantly increase faculty competitiveness.

描述（由申请人提供）：此申请的目的是 在神经科学中建立卓越生物医学研究中心（COBRE） 在佛蒙特大学（UVM）。该提案的具体目的是： 特定目的1：建立研究和智力基础设施 在UVM上支持大学范围内的神经科学卓越中心。目标 此目的包括：1）建立指导计划以支持初级 神经科学教师； 2）建立成像/生理核心以支持 初级教师的研究项目； 3）建立一个 蜂窝/分子核心支持初级研究项目 学院; 4）建立大学范围内的神经科学研讨会系列和 年度神经科学静修； 5）建立沟通机制 在促进发展的基础科学家和临床医生之间 转化研究和6）建立一个大学范围的机制 神经科学研究生教育。 特定目的2：支持核心少年核心的研究开发 将成为神经科学卓越中心的未来领导者的教师。 受到支持的教师，他们的项目头衔是：1）Rona Delay博士， 生物学系：嗅觉神经元中的氯化物稳态； 2）博士 William Falls，心理学系：分子和遗传分析 学会了减少小鼠的恐惧； 3）Anthony Morielli博士，部门 药理学：钾通道的激酶和细胞骨架调节； 4）博士 马修·兰德（Matthew Rand），解剖学和神经生物学系：蛋白水解调节 神经发生中的Notch信号传导和5）乔治·威尔曼（George Wellman）博士 药理学：亚蛛网膜下腔出血中脑血管痉挛的机制。 UVM在神经科学三个领域建立了研究人员： 分子/发育，细胞/系统和临床/行为 神经科学。此申请的裁决将为 在这些现有神经科学领域的研究力量显着扩大 强调，将基本与临床神经科学融为一体并促进 研究范围内的研究合作。卓越研究水平 如果没有外部支持，就无法培养培训。 初级和高级研究人员的生产力将受到刺激，并且 将创建长期指导框架。 UVM是一个小型机构 资源有限的农村国家；奖项将大大扩大我们的 研究基础设施并显着提高教师的竞争力。