Blood Systems in Coagulation and Vessel Disease

血液系统在凝血和血管疾病中的作用

• 批准号: 7006620
• 负责人: Linda K Curtiss
• 金额: $ 33.35万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 1976
• 资助国家: 美国
• 起止时间: 1976-07-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7006620
• 关键词: Blood; Systems; Coagulation; Vessel; Disease

DESCRIPTION (provided by applicant): This training grant has been an excellent and productive program for 25 years. It will continue to provide the same high quality postdoctoral training in biomedical research in Blood Systems in Coagulation and Vessel Disease. This training grant will provide more than 25 postdoctoral fellows the opportunity to train for one to three years in 20 different research programs whose Principal Investigators devote 100 percent of their time to basic research. Trainees are recruited via multiple routes to attract as many candidates as possible from diverse ethnic, geographic and scientific disciplines. Study of cellular and soluble components of the vasculature is the unique cohesive theme of this NHLBI program. Functional aspects of hemostasis and blood vessel disease are studied in blood proteins, platelets, leukocytes and tissues. The common goal of the carefully chosen faculty is to understand at a basic molecular level how the vasculature functions to transport, regulate and protect the whole organism. This goal will be pursued through interdisciplinary collaborations among investigators in three different departments within the Institute. Special emphasis will be placed on use of new emerging disciplines including knock out and transgenic animals, intracellular signaling pathways, gene array approaches, protenomics and saturation mutagenesis. The success of this program has been excellent. The training experience is and will continue to be competitive and geared toward the development of self-directed researchers, yet will be enriched by cooperation and communication among scientists of diverse backgrounds.

描述（由申请人提供）： 这项培训补助金已经是一项出色而富有成效的计划，已有25年了。 它将继续提供相同的高质量博士后培训 血液系统中的生物医学研究和血管疾病。这 培训赠款将为25多个博士后研究员提供机会 在20个不同的研究计划中训练一到三年 首席研究人员将100％的时间投入基础研究。 通过多种路线招募受训人员，以吸引与尽可能多的候选人 可能来自不同的种族，地理和科学学科。研究 脉管系统的细胞和可溶性成分是独特的内聚力 这个NHLBI计划的主题。止血和血液的功能方面 血管疾病在血蛋白，血小板，白细胞和 组织。精心选择的教师的共同目标是在 脉管系统如何运输，调节的基本分子水平 并保护整个生物体。这个目标将通过 三种不同的研究人员之间的跨学科合作 研究所内的部门。特别重点将放在使用 新的新兴学科，包括敲除和转基因动物， 细胞内信号通路，基因阵列接近，质子学和 饱和诱变。该计划的成功非常出色。这 培训经验是并且将继续具有竞争力并致力于 自我指导的研究人员的发展，但会被 不同背景的科学家之间的合作与沟通。