NM Minority Based Community Clinical Oncology Program

新墨西哥州少数民族社区临床肿瘤学计划

• 批准号: 7122049
• 负责人: Claire F. Verschraegen
• 金额: $ 47.64万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-17 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7122049
• 关键词: Hispanic Americans; Native Americans; cancer prevention; clinical research; clinical trials; cooperative study; health care service availability; health services research tag; human subject; human therapy evaluation; medical outreach /case finding; medically underserved population; neoplasm /cancer; neoplasm /cancer education; neoplasm /cancer epidemiology; neoplasm /cancer therapy; patient oriented research

DESCRIPTION (provided by applicant): The State of New Mexico is characterized by ethnic diversity and unusual patterns of cancer incidence and mortality. A substantial number of New Mexicans are young, rural, poor, and medically uninsured and underserved. With a higher percentage of Hispanics and Native Americans than any other State, New Mexico's 1.8 million citizens are 45% White, 42% Hispanic, 10% Native American, 2% Black, and 1% other ethnic minorities. In addition to English and Spanish, our Pueblo, Navajo, Apache, and Ute Indian Tribes speak over twenty different languages and dialects. In this context, the mission of the University of New Mexico Cancer Research and Treatment Center (UNM CRTC) is to use its expertise in basic, translational, and clinical cancer research, cancer epidemiology, and community intervention to reduce the incidence and mortality of cancer in New Mexico's multiethnic populations. Participation in cooperative cancer prevention and treatment trials sponsored by the National Cancer Institute (NCI) and the MB-CCOP program, is a critical part of this mission. CRTC investigators have been contributing patients and scientific expertise to the NCI program since the Center opened in 1975. Currently funded with an NCI P20 Cancer Center Planning Grant, the CRTC has excellent research and primary cancer prevention programs supported by $83 million in total peer-reviewed funding. Among these is the New Mexico Tumor Registry (NMTR), one of the original Surveillance, Epidemiology and End Results (SEER) programs, now in its 30th year of NCI funding. The NMTR holds the world's largest database on cancer incidence and mortality in Hispanics and Native Americans and has documented strikingly different patterns of cancer incidence and mortality in these groups. Funded under the the MB-CCOP program since August 2000, the CRTC is building strong clinical cancer programs through the recruitment of 14 new oncology clinical specialists and the development of a new expanded clinical trials infrastructure at UNM and its affiliate sites. Together, the UNM CRTC and its Affiliates serve 80% of the cancer patients in the State. In close parallel with New Mexico's ethnic diversity, 52% of the patients currently enrolled from our MB-CCOP program to NCl-sponsored treatment and prevention trials are ethnic minorities: 31% Hispanic, 16% American Indian, 4% Asian, and 1% Black. Prior to being funded as a MB-CCOP program, the CRTC was a member institution of the Southwest Oncology Group (SWOG) and the Pediatric Oncology Group (POG); CRTC faculty continue to play significant leadership roles in these groups. Additional Research Bases include the National Surgical Adjuvant Breast and Bowel Project (NSABP) and most recently, the Eastern Cooperative Oncology Group (ECOG). Renewed funding of this MB-CCOP program will insure increased access and accrual of minorities to clinical trials, strengthen our Affiliate Network, facilitate the building of clinical trials programs with Hispanic and Native American Tribes and communities, and expand outreach to minority populations and the medically underserved in our region.

描述（由申请人提供）：新墨西哥州的特点是种族多样性和癌症发病率和死亡的异常模式。大量新墨西哥人是年轻，农村，贫穷，医学上没有保险和服务不足的人。新墨西哥州的180万公民比其他任何州都高于西班牙裔和美洲原住民的比例，是45％的白人，42％的西班牙裔，10％的美国原住民，2％黑人和1％的其他少数民族。除了英语和西班牙语外，我们的pueblo，navajo，apache和ute印度部落都会讲二十多种不同的语言和方言。在这种情况下，新墨西哥大学癌症研究与治疗中心（UNM CRTC）的任务是在基本，转化和临床癌症研究，癌症流行病学和社区干预方面使用其专业知识来降低新墨西哥州多种族种群的癌症的发生率和死亡率。参与由国家癌症研究所（NCI）和MB-CCOP计划赞助的预防癌症预防和治疗试验，是该任务的关键部分。自1975年中心开业以来，CRTC的研究人员一直在为NCI计划提供贡献的患者和科学专业知识。目前由NCI P20癌症中心计划拨款提供资金，CRTC拥有出色的研究和初级预防癌症预防计划，由8300万美元的同行评估资金提供了8300万美元。其中包括新墨西哥肿瘤登记局（NMTR），这是最初的监视，流行病学和最终结果（SEER）计划，现在是NCI资助的第30年。 NMTR持有西班牙裔和美洲原住民癌症发病率和死亡率的世界最大数据库，并记录了这些群体中癌症发病率和死亡率的明显不同。 CRTC自2000年8月以来就根据MB-CCOP计划资助，通过招募14位新的肿瘤学临床专家以及在UNM及其会员站点开发新的扩展临床基础设施，建立强大的临床癌症计划。联合国CRTC及其分支机构共同为该州80％的癌症患者服务。与新墨西哥州的种族多样性密切相关，目前有52％的患者从我们的MB-CCOP计划到NCL赞助的治疗和预防试验是少数民族：31％的西班牙裔西班牙裔，16％的美洲印第安人，4％的亚洲人和1％的黑人。在作为MB-CCOP计划资助之前，CRTC是西南肿瘤学集团（SWOG）和小儿肿瘤学集团（POG）的成员机构； CRTC教师继续在这些小组中扮演重要的领导角色。其他研究基础包括国家手术辅助乳房和肠项目（NSABP），以及最近的东部合作肿瘤学小组（ECOG）。该MB-CCOP计划的新资金将确保少数群体对临床试验的访问和应计，增强我们的会员网络，促进与西班牙裔和美洲原住民部落和社区建立临床试验计划，并将外展扩展到少数民族人群以及在我们地区的医学上不受欢迎。