A Mechanical/Neural Limb Prosthetic Interface

机械/神经假肢接口

• 批准号: 6620218
• 负责人: Harold Alexander
• 金额: $ 25.17万
• 依托单位: BIOLOK INTERNATIONAL, INC.-ORTHOGEN CORP
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-08 至 2005-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6620218
• 关键词: biomaterial interface interaction; biomechanics; bone prosthesis; electrodes; electronic recording system; implant; laboratory rabbit; laboratory rat; limbs; medical implant science; nervous system prosthesis; neuromuscular function; neuromuscular stimulator; skeletal prosthesis

DESCRIPTION (Provided by Applicant): Each year over 6,100 Americans undergo upper limb amputation requiring the use of prosthetic devices. With current devices, the patient is unable to mechanically and electrically control the prosthetic to mimic normal function. When nerves are severed or disrupted, the information for control is still present. A better, more natural control of the prosthesis could be achieved if that information could be used to operate a prosthesis. To-date, no stable, reliable interface between the electronics of the prosthesis and the nervous system exists. Additionally, soft tissue, press-fit attachment to the stump is less than ideal. Skeletal attachment of the device would greatly facilitate mechanical control and utility. The primary objective of this project is to demonstrate the feasibility of a skeletally attached interface that can effect both mechanical and electrical control. A peripheral nerve interface has been developed in which slips of muscle are isolated from a host muscle in the environment of a recording electrode. A combined transcutaneous port/skeletal attachment device, has been developed with surface microtexturing that allow a stable connection of skin, connective tissues and bone to its surface. The proposed experiments are designed to validate aspects of both parts of the system, leading to its practical utility.

描述（由申请人提供）：每年有超过 6,100 名美国人接受 需要使用假肢装置的上肢截肢。有电流 设备，患者无法机械和电气控制 模仿正常功能的假肢。当神经被切断或扰乱时， 控制信息仍然存在。更好、更自然的控制 如果该信息可用于操作假肢，则可以实现假肢 假肢。迄今为止，电子设备之间还没有稳定、可靠的接口 假肢和神经系统存在。此外，软组织、 与树桩的压配合连接不太理想。骨骼附着 该装置将极大地促进机械控制和实用性。初级 该项目的目的是证明骨骼结构的可行性 附加接口可实现机械和电气控制。一个 已开发出周围神经接口，其中肌肉滑动 在记录电极的环境中与宿主肌肉分离。一个 已开发出组合式经皮端口/骨骼附着装置 具有表面微纹理，可实现皮肤、结缔组织的稳定连接 组织和骨骼到其表面。所提出的实验旨在 验证系统两个部分的各个方面，从而实现其实用性。