Native Healthy Lifestyle: A Return to Balance

本土健康生活方式：回归平衡

• 批准号: 7209268
• 负责人: ELISA TAN LEE
• 金额: $ 39.72万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7209268
• 关键词: Native Americans; behavior modification; behavioral /social science research tag; blood chemistry; body composition; caloric dietary content; cardiovascular disorder; cardiovascular disorder prevention; cardiovascular disorder risk; clinical research; clinical trials; diet; health behavior; health surveys; human middle age (35-64); human subject; human therapy evaluation; interview; longitudinal human study; medically underserved population; nutrition; nutrition related tag; physical fitness; sodium

DESCRIPTION (provided by applicant): Only decades ago cardiovascular disease (CVD) was rare in American Indians, but today it has become the leading cause of death for this population, exceeding rates in the general population. To reduce cardiovascular risk, we propose a holistic behavioral and lifestyle intervention program that is community-responsive and culturally appropriate. This intervention program will primarily focus on behavioral modification in diet and physical activity, which will lead to improvement of CVD risk factors and consequently reduction of CVD. The specific aims are: 1. To design and implement a culturally appropriate behavioral intervention program for American Indian adults (aged 30-59 years), who have high risk of developing CVD, to form healthy habits in diet and physical activity. 2. To evaluate the effectiveness of the proposed behavioral intervention program using a two-arm randomized controlled design. Two hundred eligible American Indian men and women will be randomized into two groups: (1) "intervention" groups, which receives the proposed intervention program, and (2) "control" group, which receives conventional cardiovascular health information and advice only. Two sets of outcome measures will be used to compare the two groups. The primary outcome measures will be behavioral modification outcomes, including caloric intake, sodium intake and fruit and vegetable consumption for diet and pedometer measurements for physical activity. The secondary outcome measures are CVD risk factor measures, including weight (or BMI), total triglyceride, HDL-cholesterol, LDL-cholesterol, HbA1c, fasting glucose, blood pressure and urinary albumin/creatinine ratio. 3. If successful, disseminate the intervention program to other American Indian tribes and communities for implementation. We hypothesize that participants in the intervention group will improve their caloric and sodium intake and increase fruit and vegetable consumption and physical activity when compared to the control group. The proposed intervention emphasizes achieving spiritual, mental, emotional and physical balance, which are elements of traditional American Indian wellness and vitality. The proposed intervention program is developed with much input from the Indian community and can be incorporated into tribal health programs. We believe it has a high probability of success and is highly sustainable in the community after the termination of this research study.

描述（由申请人提供）： 几十年前，心血管疾病 (CVD) 在美洲印第安人中还很罕见，但如今它已成为该人群的首要死因，超过了普通人群的发病率。为了降低心血管风险，我们提出了一项响应社区需求且适合文化的整体行为和生活方式干预计划。该干预计划将主要侧重于饮食和体力活动的行为改变，这将改善 CVD 危险因素，从而减少 CVD。具体目标是： 1. 为心血管疾病高风险的美国印第安成年人（30-59岁）设计并实施符合文化的行为干预计划，以形成健康的饮食和身体活动习惯。 2. 使用双臂随机对照设计评估所提出的行为干预计划的有效性。 200 名符合条件的美国印第安人男性和女性将被随机分为两组：(1)“干预”组，接受拟议的干预计划；(2)“对照组”，仅接受传统的心血管健康信息和建议。将使用两组结果测量来比较两组。主要结果指标将是行为改变结果，包括饮食中的热量摄入、钠摄入量和水果和蔬菜消耗以及体力活动的计步器测量。次要结果指标是 CVD 危险因素指标，包括体重（或 BMI）、总甘油三酯、HDL 胆固醇、LDL 胆固醇、HbA1c、空腹血糖、血压和尿白蛋白/肌酐比。 3. 如果成功，将干预计划传播给其他美洲印第安部落和社区实施。 我们假设与对照组相比，干预组的参与者将提高热量和钠的摄入量，并增加水果和蔬菜的摄入量和体力活动。拟议的干预措施强调实现精神、心理、情感和身体平衡，这是传统美洲印第安人健康和活力的要素。拟议的干预计划是根据印第安社区的大量意见制定的，可以纳入部落健康计划。我们相信，在本研究结束后，它成功的可能性很高，并且在社区中具有高度的可持续性。