Emotional Expression and Cancer Caregivers

情绪表达和癌症护理人员

• 批准号: 7102304
• 负责人: Shelby Langer
• 金额: $ 16.96万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7102304
• 关键词: Internet; blood; buffers; caregivers; clinical research; conditioning; coping; emotions; exercise; face; hematopoietic stem cells; hospitals; neoplasm /cancer; questionnaires

DESCRIPTION (provided by applicant): This twice revised proposal, in response to PA-04-034, Exploratory Grants for Behavioral Research in Cancer Control, focuses on spousal caregivers (CGs) of hematopoietic stem cell transplant survivors - persons known to report elevated levels of distress as compared to both norms and their patient counterparts. Specific Aims are to: (1) Determine, via experimental manipulation, whether or not CGs of hematopoietic stem cell transplant patients engage in protective buffering, a coping mechanism whereby partners shield patients from illness-related concerns or worries, (2) Examine synchrony or lack thereof, desynchrony, among subjective, expressive and biologic indicators of emotion among spousal CGs, and (3) Test the feasibility and implementation of an emotional expression (EE) exercise designed to enhance psychological and immune functioning among spousal CGs. One-hundred and seventeen patient/ spouse dyads will be recruited for the study. Patients and CGs will complete baseline assessments (questionnaires) 4-6 days after the patient's discharge from the hospital; CGs will provide blood samples to analyze TNF- alpha and IL-6. CGs will then be randomly assigned to one of three conditions: EE with the patient present, EE with the patient absent, or a control condition. For the latter, CGs will talk about positive experiences and time management. For all sessions, CGs will talk for 10 minutes on 3 consecutive days, with verbal and nonverbal expressions recorded and concurrent galvanic skin response collected. Follow-up assessments will occur immediately following the third EE session (questionnaires) and again in two months (questionnaires and CG blood draw). This R21 serves as a feasibility/ social laboratory test of methods and measures, intervening with CGs at their greatest time of need. There exists a lack of resources for these CGs. Findings will determine whether CGs benefit from an opportunity to express their emotions, alone and/or in the presence of their patient. If, as hypothesized, CGs benefit from the opportunity to express in the absence of their patient, future research can test methods for such opportunities: written, verbal, face-to-face or internet. If CGs benefit from the opportunity to express in the presence of their patient, dyadic interventions may be warranted. In short, findings from this study can serve as a springboard for future research investigations and, ultimately, clinical interventions.

描述（由申请人提供）：此两次修订的提案是为了回应 PA-04-034（癌症控制行为研究探索性资助），重点关注造血干细胞移植幸存者的配偶照顾者 (CG) - 已知报告水平升高的人与正常人和患者相比，他们感到痛苦。具体目标是：（1）通过实验操作确定造血干细胞移植患者的 CG 是否参与保护性缓冲，这是一种应对机制，合作伙伴可以通过该机制保护患者免受与疾病相关的担忧或担忧，（2）检查同步性或配偶 CG 中情绪的主观、表达和生物指标之间缺乏、不同步，以及 (3) 测试旨在增强心理和免疫功能的情绪表达 (EE) 练习的可行性和实施配偶CG。该研究将招募一百一十七名患者/配偶。患者和CG将在患者出院后4-6天完成基线评估（问卷）； CG 将提供血样来分析 TNF-α 和 IL-6。然后，CG 将被随机分配给以下三种条件之一：患者在场的 EE、患者不在场的 EE 或对照条件。对于后者，CG 将谈论积极的体验和时间管理。对于所有会议，CG 将连续 3 天进行 10 分钟的演讲，记录言语和非言语表达，并收集并发的皮肤电反应。后续评估将在第三次 EE 会议（调查问卷）后立即进行，并在两个月后再次进行（调查问卷和 CG 抽血）。该 R21 作为方法和措施的可行性/社会实验室测试，在 CG 最需要的时候进行干预。这些 CG 缺乏资源。研究结果将确定 CG 是否能从单独和/或在患者在场的情况下表达情绪的机会中受益。如果正如假设的那样，CG 受益于在患者不在场的情况下表达的机会，未来的研究可以测试这种机会的方法：书面、口头、面对面或互联网。如果 CG 受益于在患者面前表达的机会，则可能需要进行二元干预。简而言之，这项研究的结果可以作为未来研究调查以及最终临床干预的跳板。