Phase II: U.S. Mexico Border Diabetes Prevention and Control Project

第二期：美墨边境糖尿病防治项目

• 批准号: 7252194
• 负责人: Maria Teresa Cerqueira
• 金额: $ 53.9万
• 依托单位: PAN AMERICAN HEALTH ORGANIZATION
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7252194
• 关键词: Mexican Americans; Mexico; clinical research; community health services; cooperative study; cost effectiveness; diabetes education; diabetes mellitus therapy; education evaluation /planning; health behavior; human subject; noninsulin dependent diabetes mellitus

DESCRIPTION (provided by applicant): Diabetes is a leading cause of death in both the United States and Mexico, and the third leading cause of death in the US-Mexico border region. Although the exact cause of the disease is unknown, and no cure is forthcoming in the near future, it is known that besides genetic predisposition, a number of environmental, economic, social, and cultural factors and barriers may also contribute to this high prevalence rate. To deal with these factors and barriers the United States Mexico Border Diabetes Prevention and Control Project (USMBDPCP) is proposing to implement and evaluate a family-based participatory intervention delivered by Community Health Workers/Promotores de Salud (CHWs/PS) to help increase the knowledge of appropriate and effective prevention, and control strategies to improve the management of diabetes care among border populations. The USMBDPCP will evaluate the intervention against the standard diabetes care provided in the community, and will also assess the cost effectiveness of its implementation. If considered successful, the proposed model will be marketed as a viable intervention model to be implemented in communities and health-care systems along the US-Mexico Border region. Almost 2,000 participants (660 patients and 1.320 family members) will be recruited in eleven selected communities along the US-Mexico border. At each site, half of the participants will be randomly enrolled in the proposed intervention and half in a standard diabetes intervention control group. The research questions to be answered deal with the effectiveness of the intervention, specifically an increase in the number of patients monitoring their blood level, the improvement in the hemoglobin A1C levels and lipid profiles of patients, how the inclusion of the family, or other factors helped improve disease outcomes, and if the intervention was cost-effective. The intervention implementation process and procedures will be documented and all materials will be made available to CDC for dissemination and replication in other border areas and among other Hispanic populations throughout both countries.

描述（由申请人提供）：糖尿病是美国和墨西哥的主要死亡原因，也是美国 - 墨西哥边境地区的第三大死亡原因。 尽管该疾病的确切原因尚不清楚，并且在不久的将来无法治愈，但众所周知，除了遗传易感性外，许多环境，经济，社会和文化因素以及障碍也可能导致这种高流行率。 为了应对这些因素和障碍，美国墨西哥边境糖尿病预防和控制项目（USMBDPCP）提议实施和评估社区卫生工作者/促销员De Salud（CHWS/PS）提供的基于家庭的参与性干预措施，以帮助提高适当和有效的预防知识，并控制对糖尿病领域的管理策略，以改善对边界群体的管理层护理。 USMBDPCP将评估针对社区提供的标准糖尿病护理的干预措施，并将评估其实施的成本效益。 如果被认为是成功的，则建议的模型将作为可行的干预模型销售，将在美国 - 墨西哥边境地区沿线的社区和医疗保健系统中实施。 将在美国 - 墨西哥边境沿线的11个社区中招募近2,000名参与者（660名患者和1.320个家庭成员）。 在每个地点，一半的参与者将随机参与建议的干预措施，一半参与者参与者，其中一半是标准糖尿病干预对照组。 要回答的研究问题涉及干预措施的有效性，特别是监测血液水平的患者人数的增加，血红蛋白A1C水平的提高和患者的脂质谱，家庭的包含或其他因素如何帮助改善疾病的结果，以及干预措施是否具有成本效益。 将记录干预实施过程和程序，并将所有材料提供给CDC，以在其他边境地区以及两国的其他西班牙裔人口中进行传播和复制。