Computer-based vs Interpersonal HIV preventive intervent

基于计算机的艾滋病毒预防干预与人际艾滋病预防干预

• 批准号: 6876353
• 负责人: Marguerita A. Lightfoot
• 金额: $ 56.49万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6876353
• 关键词: AIDS education /prevention; DVD /CD ROM; HIV infections; academic achievement; adolescence (12-20); behavioral /social science research tag; clinical research; clinical trials; computer assisted instruction; conduct disorder; criminal behavior; education evaluation /planning; educational resource design /development; employment /unemployment; high risk behavior /lifestyle; human subject; interpersonal relations; interview; juvenile delinquency; longitudinal human study; secondary schools; sex behavior; substance abuse related disorder; violence

DESCRIPTION (provided by applicant): Adolescents' contact with the criminal justice system is associated with a number of long-term negative adult outcomes: unemployment, substance abuse, and incarceration (Moffitt, 2002). The most recent statistics indicate that nationally, there are at least 634,100 youth on probation and 39,000 youth in LA County are on probation (Office of Juvenile Justice & Delinquency Prevention, 1999). Delinquent youth on probation have multiple sexual partners, frequent unprotected sexual risk acts, high rates of sexually transmitted diseases and substance use, as well as gang involvement (Morris et al., 1995). HIV prevention is highly efficacious with adolescents (NIH, 1997); however, a successful program has not been developed for these youth. Building on the results of three efficacious HIV prevention programs with those at high HIV risk (CDC, 2001; LIGHT, Adolescent LIGHT, & Street Smart) and the PI's recent R21 project, this proposal aims to examine the relative efficacy of LIGHT in an interpersonal or a computerized delivery format, in contrast to a standard care HIV prevention condition. This application is in response to a request for applications (RFA-DA-04-012) to address critical gaps in research on HIV/AIDS prevention, treatment, and related health issues among highly vulnerable youth. The project will proceed in two phases. During Phase 1, the existing computerized LIGHT prevention program will be enhanced further to further ensure acceptability, assessment measures will be finalized and programmed on a combination ACASI/CAPI program, and 1KB applications finalized within each school, recruitment scripts and tracking programs finalized, and orientation sessions conducted for all school personnel, parents, and stakeholders. The main intervention trial, Phase 2, will utilize a complete randomized block design with youth recruited over a two-year period. Twenty four schools (n=960 students) in the Los Angeles Department of Education will be randomly assigned into one of three experimental conditions: 1) Interpersonal Light in 8 schools; 2) Computerized Light in 8 schools (n=320 youth); or 3) a standard HIV control condition. Youth in each condition will be assessed at a baseline interview, and reassessed longitudinally at 3, 6, and 12 months. The results of this study will inform researchers and the public health community about the generalizability of an HIV preventive intervention and feasibility and acceptability of an interpersonal intervention delivered in classrooms compared to delivery on a CD-ROM at computers within each classroom.

描述（由申请人提供）： 青少年与刑事司法系统的接触与许多长期的负面成人结果有关：失业、药物滥用和监禁（Moffitt，2002）。 最新统计数据表明，全国至少有 634,100 名青少年处于缓刑状态，洛杉矶县有 39,000 名青少年处于缓刑状态（青少年司法和犯罪预防办公室，1999 年）。 缓刑期间的犯罪青年有多个性伴侣，经常发生无保护的危险性行为，性传播疾病和药物滥用的发生率很高，并且参与帮派（Morris 等，1995）。 艾滋病毒预防对于青少年非常有效（NIH，1997）；然而，尚未为这些年轻人制定成功的方案。 该提案以三项针对艾滋病毒高风险人群的有效艾滋病毒预防计划（CDC，2001；LIGHT、青少年 LIGHT 和 Street Smart）的结果以及 PI 最近的 R21 项目为基础，旨在检验 LIGHT 在人际交往中的相对功效。或计算机化的交付形式，与标准护理艾滋病毒预防条件形成对比。 本申请是为了响应一项申请请求 (RFA-DA-04-012)，旨在解决高度脆弱青年中艾滋病毒/艾滋病预防、治疗和相关健康问题研究中的关键差距。 该项目将分两个阶段进行。 在第一阶段，现有的计算机化 LIGHT 预防计划将进一步增强，以进一步确保可接受性，评估措施将最终确定并在 ACASI/CAPI 组合计划上进行编程，并在每所学校内最终确定 1KB 申请，最终确定招募脚本和跟踪计划，以及为所有学校人员、家长和利益相关者举办迎新活动。 主要干预试验第二阶段将采用完全随机区组设计，在两年内招募青少年。 洛杉矶教育部的 24 所学校（n = 960 名学生）将被随机分配到以下三个实验条件之一：1）8 所学校的人际之光； 2) 8所学校配备电脑灯（n=320名青少年）；或 3) 标准 HIV 控制条件。 每种情况下的青少年都将在基线访谈中接受评估，并在 3、6 和 12 个月时纵向重新评估。 这项研究的结果将使研究人员和公共卫生界了解艾滋病毒预防干预措施的普遍性，以及在教室中进行人际干预与在每个教室的计算机上通过 CD-ROM 进行干预相比的可行性和可接受性。