RENOVATIONS FOR AUTOCLAVE SUPPORT SERVICE

高压灭菌器改造支持服务

• 批准号: 6755689
• 负责人: NORMAN H EDELMAN
• 金额: $ 40万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6755689
• 关键词: SCID mouse; animal care; animal welfare research; athymic mouse; biomedical equipment purchase; building /facility design /renovation; genetically modified animals; health science research support; laboratory mouse; nonbiomedical equipment; veterinary science

DESCRIPTION (provided by applicant): The general objective of this project is to provide support and care for the use of transgenic, SCID, knockout, immunocompromised and pathogen free mice at the Stony Brook University (SBU). The institution has both short term and long-term goals to improve animal care and services for the faculty. This grant will purchase equipment, and perform minor renovations for equipment installation, to upgrade autoclave support services in the Health Sciences Center - Division of Laboratory Animal Resources. Eighteen basic and clinically applied research laboratories, who conduct research in gene identification, mapping, analysis and regulation; bacterial and viral receptor regulation; targeted gene therapy; infectious disease pathogenesis; oncology; cerebral amyloid angiopathy; vaccine development; and membrane transport, currently house maximum isolation rodents who require sterilized equipment. The grant will purchase one 99 cu. ft, double door autoclave and two clean steam generators. Minor renovations in existing autoclave and mechanical support areas are required for equipment installation. This support equipment will improve the care of pathogen free animals and address expanding research program needs by providing essential sterilized equipment for maximum isolation housing and reducing occupational health risks and labor costs for animal care personnel through centralization of autoclaving service.

描述（由申请人提供）： 该项目的总体目标是为石溪大学 (SBU) 使用转基因、SCID、基因敲除、免疫功能低下和无病原体小鼠提供支持和护理。该机构的短期和长期目标都是改善动物护理和教职员工服务。这笔赠款将购买设备，并对设备安装进行小型翻新，以升级健康科学中心 - 实验动物资源部的高压灭菌器支持服务。十八个基础和临床应用研究实验室，开展基因鉴定、绘图、分析和调控研究；细菌和病毒受体调节；靶向基因治疗；传染病发病机制；肿瘤学；脑淀粉样血管病;疫苗开发；和膜运输，目前容纳了最多需要消毒设备的隔离啮齿动物。 这笔赠款将购买一台 99 立方米。英尺，双门高压灭菌器和两台清洁蒸汽发生器。设备安装需要对现有高压釜和机械支撑区域进行小规模改造。该支持设备将改善对无病原体动物的护理，并通过提供基本的无菌设备来实现最大程度的隔离住房，并通过集中高压灭菌服务降低动物护理人员的职业健康风险和劳动力成本，满足不断扩大的研究计划需求。