Regulatory and functional RNAs: computational approaches

调控和功能 RNA：计算方法

• 批准号: 6687991
• 负责人: Elena Rivas
• 金额: $ 4.18万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-03 至 2004-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6687991
• 关键词: RNA; functional /structural genomics; informatics; travel; workshop

DESCRIPTION: We propose to organize a workshop entitled "Regulatory and functional RNAs: computational, genomic, and structural approaches". The workshop will take place from July 27th to August 8th, 2003 in Benasque, Huesca, Spain. The workshop will have a strong focus on computational methods for the discovery and analysis of functional and regulatory RNAs in whole-genome analyses. The main goal of this workshop is to bring together the leaders in the field of RNA informatics in order to identify significant new tools, methods and algorithms that will shape the field in the near future. The expected participants will be mostly computational biologists who have already shown significant contributions in RNA bioinformatics. The primary topics of discussion will be: (1) Computational methods for the discovery of novel RNA genes and tools for the systematic genomic annotation of RNA genes. (2) Algorithms for the prediction of two and three dimensional RNA structures. Inference of RNA function. (3) RNA structural alignments and homology searches. How to improve RNA similarity searches by taking into account the structure as well as the sequence information.

描述：我们建议组织一个题为“调控和功能 RNA：计算、基因组和结构方法”的研讨会。 该研讨会将于2003年7月27日至8月8日在西班牙韦斯卡省贝纳斯克举行。 该研讨会将重点关注全基因组分析中功能性和调控性 RNA 的发现和分析的计算方法。 本次研讨会的主要目标是汇集 RNA 信息学领域的领导者，以确定在不久的将来将塑造该领域的重要新工具、方法和算法。 预期的参与者将主要是已经在 RNA 生物信息学领域做出重大贡献的计算生物学家。 讨论的主要主题是：（1）发现新RNA基因的计算方法和对RNA基因进行系统基因组注释的工具。 (2) 二维和三维RNA结构预测算法。 RNA功能的推断。 (3)RNA结构比对和同源性搜索。 如何通过考虑结构和序列信息来改进 RNA 相似性搜索。