Gordon Conference on Synaptic Transmission

戈登突触传递会议

• 批准号: 6889574
• 负责人: STEPHEN J REDMAN
• 金额: --
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6889574
• 关键词: computational neuroscience; meeting /conference /symposium; neural information processing; neural plasticity; neural transmission; neurotransmitter transport; synapses; travel

DESCRIPTION (provided by applicant): The synapse serves as the basic signaling unit of the nervous system, and synaptic transmission is relevant to most neurological diseases, as well as to mental illness, drug addiction, learning, memory, developmental disorders, pain, vision, and aging related dementias. Although the concept of the synapse has been with us for a century, recent years have seen unparalleled progress in our understanding of synapses, spawned by new molecular and biophysical technologies. These new approaches have helped to refocus the interests of neuroscientists on the basic topic of electrical and chemical signaling between excitable cells. The convergence of these new approaches has created a need for forums for the exchange of ideas between researchers from diverse disciplines that have been drawn to this topic. The Gordon Conference on Synaptic Transmission helps to fill this need. This meeting has been held under the immensely successful and popular format of Gordon Research Conferences, which are typically biyearly events. The insular setting, close contact, and relaxed atmosphere of Gordon Conferences encourage discussion and exchange of ideas between researchers, and promotes contact between speakers and attendees, including a diverse group of students, post-docs, and faculty. The first two Gordon Conferences on Synaptic Transmission (1998 and 2000) were hugely popular, and the meeting is planned to continue for at least another three cycles. The meeting is organized into eight sessions plus two plenary lectures. The sessions will cover topics that include aspects of pre- and postsynaptic mechanisms, retinal transmission, synaptic circuitry, synaptic plasticity, pain, synaptic computations, and translational research. The sessions will be connected not only through the common theme of the synapse, but also through the cutting edge techniques of molecular biology, genetics, patch clamping, and optical Imaging. The 30 principal speakers and 8 discussion leaders will be at the forefront of research in these fields, and will give in-depth presentations on complex emerging issues. This proposal is for support for the meeting in years 2002, 2004, and 2006, and the basic format for the meeting will be similar for each of those years. In 2002, the plenary lectures will be given by Nobel Laureate Bert Sakmann and Eve Marder. These lectures will set the tone for the sessions, which are designed to explore both the biophysical mechanisms of synaptic transmission, as well as the role of the synapse in neural circuit behavior. The meeting will generate a thorough discussion, while maintaining a clear focus on synaptic transmission.

描述（由申请人提供）：突触作为基本信号传导 神经系统的单位，突触传递与大多数 神经系统疾病，以及精神疾病、毒瘾、学习、记忆、发育障碍、疼痛、视力和衰老相关的痴呆症。 尽管突触的概念已经存在一个世纪了，但最近 多年来，我们对突触的理解取得了无与伦比的进步，催生了 通过新的分子和生物物理技术。这些新方法帮助了 将神经科学家的兴趣重新集中在电学的基本主题上 以及可兴奋细胞之间的化学信号传导。这些新的融合 方法需要建立论坛来交流思想 来自不同学科的研究人员被这个主题所吸引。这 戈登突触传递会议有助于满足这一需求。这 会议是在非常成功和受欢迎的形式下举行的 戈登研究会议，通常是两年一次的活动。孤岛 戈登会议的环境、密切的接触和轻松的氛围鼓励 研究人员之间进行讨论和交流，促进联系 在演讲者和与会者（包括不同的学生群体）之间， 博士后和教师。前两次戈登突触会议 Transmission（1998 年和 2000 年）非常受欢迎，会议计划 继续至少另外三个周期。本次会议共分为八个环节 分会场加两场全体会议。会议将涵盖的主题包括 突触前和突触后机制、视网膜传输、突触 电路、突触可塑性、疼痛、突触计算和翻译 研究。这些会议不仅通过共同主题联系起来 突触，而且还通过分子生物学的尖端技术， 遗传学、膜片钳和光学成像。 30位主要发言人和8位 讨论领导者将处于这些领域研究的最前沿，并且 将就复杂的新问题进行深入的演讲。这个提议是 对2002年、2004年和2006年会议的支持以及基本形式 每年的会议都是相似的。 2002年全体会议 诺贝尔奖获得者伯特·萨克曼 (Bert Sakmann) 和伊芙·马德 (Eve Marder) 将发表演讲。这些 讲座将为会议定下基调，旨在探讨 突触传递的生物物理机制，以及突触传递的作用 神经回路行为中的突触。会议将产生全面的 讨论，同时保持对突触传递的明确关注。