Conference on Molecular Regulation of Stem Cells

干细胞分子调控会议

• 批准号: 6992476
• 负责人: MARGARET A. GOODELL
• 金额: $ 0.3万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-03 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6992476
• 关键词: cell biology; embryonic stem cell; hematopoietic stem cells; meeting /conference /symposium; nerve stem cell; travel

DESCRIPTION (provided by the applicant): Stem cells continue to be of enormous scientific and clinical interest, due to the myriad therapeutic possibilities promised by their use. The initial excitement generated by identification of novel stem cell populations has given way to more focused effort on methods to manipulate their differentiation and self-renewal capacities. A number of genome-scale studies are now underway to catalog stem cell gene expression profiles or generate mouse mutants in stem cell-control genes. Coupled with more classical single gene or pathway approaches to stem cell biology, by 2005, some of the nuts-and-bolts of stem cell function should begin to be revealed. Such fundamental understanding will provide the foundation for more rapid advances toward the clinic. This conference will bring together top stem cell biologists, particularly in the areas of embryonic, neural, and hematopoietic stem cells, to discuss molecular mechanisms of stem cell function.

描述（由申请人提供）：由于其使用所承诺的无数治疗可能性，干细胞继续具有巨大的科学和临床意义。通过鉴定新的干细胞种群产生的最初兴奋已让位于更集中于操纵其分化和自我更新能力的方法上。现在正在进行许多基因组规模研究，以进行目录干细胞基因表达谱或在干细胞控制基因中产生小鼠突变体。再加上更经典的单基因或干细胞生物学的途径方法，到2005年，应开始揭示干细胞功能的某些坚果和螺栓。这种基本的理解将为诊所的进步提供基础。这次会议将汇集顶级干细胞生物学家，特别是在胚胎，神经和造血干细胞的领域，讨论干细胞功能的分子机制。