Behavioral Treatment for Dietary Adherence in Children

儿童饮食依从性的行为治疗

• 批准号: 7048362
• 负责人: SCOTT W POWERS
• 金额: $ 16.29万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-15 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7048362
• 关键词: behavior therapy; behavioral /social science research tag; child physical development; clinical research; clinical trials; cystic fibrosis; developmental nutrition; diet therapy; early /brief intervention /therapy; health care quality; human subject; human therapy evaluation; insulin dependent diabetes mellitus; longitudinal human study; nutrient intake activity; nutrition related tag; obesity; outcomes research; parent offspring interaction; patient oriented research; preschool child (1-5); quality of life; therapy compliance

DESCRIPTION (provided by applicant): The Specific Aims of this renewal application for a Midcareer Investigator Award in Patient-Oriented Research are 1) to develop and evaluate the efficacy of behavioral interventions designed to increase dietary adherence, improve health outcomes, and enhance quality of life for young children with cystic fibrosis, type 1 diabetes, and those at risk for obesity, and 2) to provide the candidate protected time and resources necessary to mentor postdoctoral fellows and junior faculty members in psychology and pediatrics who are pursuing clinical investigation in behavioral nutrition interventions for children. The Candidate's programmatic research has focused on identifying behavioral factors that compromise dietary adherence and translating this knowledge into behavioral interventions that can be tested in rigorous clinical trials. During the course of this award, the candidate will complete research studies with young children with cystic fibrosis, type 1 diabetes, and those at risk for obesity. For each population, the objective is to establish the efficacy of behavioral treatments through well-designed clinical outcome studies and disseminate the findings so that standard care for these children can be improved. The candidate also has an established track record of providing mentorship to postdoctoral fellows and junior faculty in psychology and pediatrics. The Research Plan includes two projects: an NIH/NIDDK competing continuation R01 clinical trial, "Behavioral & Nutrition Treatment to Help CF Preschoolers Grow," and a new longitudinal study focusing on "Prospective Evaluation of the Effect of Parent Feeding Strategies on Child Eating and Weight in Low-Income African American Preschoolers." In addition, the candidate will continue his research focused on dietary adherence in young children with type 1 diabetes. The Mentoring Plan for beginning clinical investigators will consist of 1) individualized mentoring of postdoctoral fellows on an NIDDK T32 training grant focused on research training in child behavior and nutrition research, 2) training and supervision of the postdoctoral fellows in the development of their own independent research proposals, and 3) participation of postdoctoral fellows in established didactic programs on manuscript and grant writing, design of clinical trials and clinical research methodology, and ethics in clinical research. Cincinnati Children's Hospital Medical Center provides an ideal setting for continuation of this award because of the commitment to patient-oriented research, the presence of a strong pediatric General Clinical Research Center, and ongoing initiatives to promote innovative clinical research including the Behavioral Core of the GCRC and the interdisciplinary training grant in Child Behavior and Nutrition Research (T32). The public health goals of the candidate's research program are to develop better treatments for young children and their families that can improve the current standard of dietary care and to train the next generation of patient-oriented researchers in this area

描述（由申请人提供）： 此次续签以患者为导向的研究中职业生涯研究者奖的具体目标是 1) 开发和评估行为干预措施的功效，这些干预措施旨在提高饮食依从性、改善健康结果并提高患有囊性纤维化的幼儿的生活质量、1 型糖尿病和肥胖风险人群，以及 2) 为候选人提供必要的受保护时间和资源，以指导正在从事行为营养干预临床研究的心理学和儿科博士后研究员和初级教员对于儿童。候选人的计划性研究重点是确定损害饮食依从性的行为因素，并将这些知识转化为可以在严格的临床试验中进行测试的行为干预措施。在获得该奖项期间，候选人将完成对患有囊性纤维化、1 型糖尿病和有肥胖风险的幼儿的研究。对于每个人群，目标是通过精心设计的临床结果研究来确定行为治疗的有效性，并传播研究结果，以便改善这些儿童的标准护理。该候选人还拥有为心理学和儿科博士后研究员和初级教师提供指导的良好记录。该研究计划包括两个项目：一项 NIH/NIDDK 竞争性延续 R01 临床试验“帮助 CF 学龄前儿童成长的行为和营养治疗”，以及一项新的纵向研究，重点是“家长喂养策略对儿童饮食和饮食的影响的前瞻性评估”。低收入非洲裔美国学龄前儿童的体重。”此外，该候选人将继续专注于 1 型糖尿病幼儿的饮食依从性研究。针对初级临床研究人员的指导计划将包括 1) 对博士后研究员进行 NIDDK T32 培训资助的个性化指导，重点关注儿童行为和营养研究方面的研究培训，2) 对博士后研究员发展其独立研究能力进行培训和监督研究提案，3) 博士后研究员参与已建立的关于手稿和拨款写作、临床试验设计和临床研究方法以及临床研究伦理的教学计划。辛辛那提儿童医院医疗中心为继续获得该奖项提供了理想的环境，因为该中心致力于以患者为导向的研究，拥有强大的儿科普通临床研究中心，并不断采取措施促进创新临床研究，包括 GCRC 的行为核心以及儿童行为和营养研究跨学科培训补助金（T32）。候选人研究计划的公共卫生目标是为幼儿及其家庭开发更好的治疗方法，以提高当前的饮食护理标准，并培训该领域的下一代以患者为中心的研究人员