CORE B--CLINICAL/BIOSTATISTICS

核心 B——临床/生物统计学

• 批准号: 6877757
• 负责人: RICHARD JOSEPH DECKELBAUM
• 金额: $ 8.31万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6877757
• 关键词: atherosclerosis; biomedical facility; cardiovascular disorder risk; clinical research; data management; human subject; mathematical model; medical outreach /case finding; statistics /biometry

DESCRIPTION (provided by the applicant): Function of the Clinical/Biostatistics Core: 1) Procurement, organization, and distribution of DNA and other samples from well characterized subjects, to service specific SCOR projects; recruitment of individuals to provide plasma and blood cells for specific SCOR projects. 2) Provision of biomathematics and biostatistics analyses in the SCOR program, including statistical analysis of genetic data, data processing and management and mathematical modeling. A major goal of the Core is to secure the DNA and blood samples subjects and analyses to define the genetic and molecular contributions to atherogenesis. This Core will fill a critical role that is required of the SCOR program in Molecular Medicine and Atherosclerosis, i.e. it will provide clinical resources (DNA, macrophages, and plasma samples) for study in the individual projects, allowing integration of basic and clinical resources. Further, the Core will facilitate collaboration among investigators, projects and cores within the Columbia University SCOR program, additional outside resources and other atherosclerosis SCOR programs.

描述（由申请人提供）： 临床/生物统计学核心的功能： 1) DNA 和其他样本的采购、组织和分发 明确的主题，为特定的 SCOR 项目服务；招募 为特定 SCOR 项目提供血浆和血细胞的个人。 2) 在SCOR程序中提供生物数学和生物统计学分析， 包括遗传数据的统计分析、数据处理和管理 和数学建模。 核心的一个主要目标是保护受试者的 DNA 和血液样本， 分析以确定遗传和分子对动脉粥样硬化的贡献。 该核心将填补 SCOR 计划所需的关键角色 分子医学和动脉粥样硬化，即它将提供临床 用于个体研究的资源（DNA、巨噬细胞和血浆样本） 项目，允许整合基础和临床资源。此外， Core 将促进研究人员、项目和核心之间的协作 在哥伦比亚大学 SCOR 计划内，额外的外部资源和 其他动脉粥样硬化 SCOR 计划。