IMPACT OF MDRI AND CYP3A4 ON PROTEASE-INHIBITOR INDUCED METABOLIC ABNORMALITIES

MDRI 和 CYP3A4 对蛋白酶抑制剂引起的代谢异常的影响

• 批准号: 7044941
• 负责人: BETTY DONG
• 金额: $ 0.08万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-12-01 至 2004-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7044941
• 关键词: AIDS therapy; HIV infections; P glycoprotein; antiAIDS agent; antiviral agents; clinical research; cytochrome P450; disease /disorder proneness /risk; drug adverse effect; gene expression; glucose tolerance; human subject; insulin sensitivity /resistance; metabolism disorder; patient oriented research; pharmacokinetics; phlebotomy; protease inhibitor