Acquisition of 800 MHz NMR System with Cryogenic Probe

使用低温探​​头采集 800 MHz NMR 系统

• 批准号: 6804174
• 负责人: GAETANO T MONTELIONE
• 金额: $ 76万
• 依托单位: UNIV OF MED/DENT NJ-R W JOHNSON MED SCH
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6804174
• 关键词: biomedical equipment purchase; cryoscience; nuclear magnetic resonance spectroscopy; proteomics

DESCRIPTION (provided by applicant): This is to request partial funding for an 800 MHz nuclear magnetic resonance (NMR) system, with cryogenic probe, for biomolecular and structural proteomics research. The balance of funding will be provided from a combination of institutional matching funds, industrial gifts, and other grant funds that have already been approved for this purpose. The 800 MHz NMR System with cryogenic probe will be used primarily for studies of protein and nucleic acid structure and dynamics, as a component of research supported largely by the National Institutes of Health. The instrument will be housed in a new 2,000 sq-ft Biomolecular NMR Facility recently constructed by the Robert Wood Johnson Medical School (RWJMS) of the University of Medicine and Dentistry of New Jersey (UMDNJ), and will be used primarily by faculty and scientists from RWJMS and Rutgers University, including members of the Center for Advanced Biotechnology and Medicine, the Cancer Institute of New Jersey, Howard Hughes Medical Institute, the Center for Integrative Proteomics Technologies, and the DIMACS Institute for Quantitative Biology. In addition, the 800 MHz NMR instrument will be made available to researchers from Cornell University, Oklahoma State University, University of Nebraska, University of Kansas, University of Vermont, and from local New Jersey - based pharmaceutical and biotechnology companies. Finally, the instrumentation will be used to support research in high-throughput protein structure production by the NIH-funded Northeast Structural Genomics Consortium.

描述（由申请人提供）：这是为生物分子和结构蛋白质组学研究的800 MHz核磁共振（NMR）系统提供部分资金。资金的余额将由机构匹配资金，工业礼物和其他已批准为此目的的资金的组合提供。具有低温探针的800 MHz NMR系统将主要用于蛋白质和核酸结构和动力学的研究，这是美国国立卫生研究院主要支持的研究组成部分。该乐器将安置在新的2,000平方英尺的生物分子NMR设施中，该设施最近由新泽西大学医学院和牙科（UMDNJ）的罗伯特·伍德·约翰逊医学院（RWJMS）建造，主要由RWJMS和RUTECERS INSTRACY的教职员工，包括新医学的研究员，以及癌症中心的成员，包括新泽西州的科学家，以及新泽西州的科学家，以及新泽西州。医学研究所，综合蛋白质组学技术中心和DIMACS定量生物学研究所。此外，康奈尔大学，俄克拉荷马州立大学，内布拉斯加州大学，堪萨斯大学，佛蒙特大学，佛蒙特大学以及新泽西州当地的制药和生物技术公司的研究人员将提供800 MHz NMR仪器。最后，该仪器将用于支持NIH资助的东北结构基因组学联盟中高通量蛋白结构生产的研究。