MONITOR HEART RATE IN MONKEYS W/NON INJURIOUS SELF DIRECTED BITINGNG

通过非伤害性自我定向咬合监测猴子的心率

• 批准号: 6591355
• 负责人: MELINDA NOVAK
• 金额: $ 11.11万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6591355
• 关键词: Mammalia; behavioral /social science research tag; carbohydrates; mental disorders; nervous system; psychology

The disorder of self-injurious behavior in monkeys is characterized with occasional bouts of wounding and frequent episodes of non-injurious biting Little is known about the functions of such behavior in rhesus monkeys; however, this disorder may persist because of some reinforcing quality such as tension reduction Evidence from human populations with this disorder (e g , prisoners who engage in cutting) provide strong support for this view To examine the tension reduction hypothesis in monkeys, we analyzed heart rate activity during episodes of non-injurious, self-directed biting (NIB) The subjects were 7 monkeys involved in heart rate testing that were observed to bite themselves (NIB) during the test The monkeys were fitted with vests containing radiotelemetry units in the afternoon and monitored for heart rate the next morning The monkeys were simultaneously videotaped to record their behavior Heart rate was analyzed in 30-second epochs We evaluat ed heart r ate in intervals prior to, during, and just after a biting episode and compared these values to the baseline heart rate Heart rate was significantly elevated during biting episodes compared to the intervals prior to and after biting Heart rate had already begun to increase in the interval prior to biting as indicated by a significant elevation compared to baseline Immediately after biting, heart rate dropped precipitously to baseline levels as would be expected according to the tension-reduction hypothesis To rule out simple locomotor explanations of the changes in heart rate, we examined a similar activity (biting the vest) and performed the same heart rate analysis Vest biting was associated with a modest, nonsignificant increase in heart rate with little change in heart rate in the following interval These results suggest that NIB can produce tension reduction which is independent of simple locomotor changes Further research will be aimed at examining stress hormone le vels in monkeys just prior to and after biting as an independent corroboration of the tension reduction hypothesis

猴子的自残行为障碍是 特点是偶尔发生伤害和频繁发作 对于非伤害性咬合的功能知之甚少 恒河猴的行为；然而，这种疾病可能会持续存在，因为 一些增强质量，例如减少张力的证据 患有这种疾病的人群（例如，从事某些活动的囚犯） 切割）为这一观点提供了强有力的支持来检验张力 猴子的减少假设，我们分析了心率活动 在非伤害性、自我导向性咬伤（NIB）发作期间 受试者是 7 只参与心率测试的猴子， 在测试过程中观察到猴子咬自己（NIB） 下午配备含有无线电遥测装置的背心， 第二天早上监测猴子的心率 同时录像记录他们的行为心率 以 30 秒为周期进行分析 我们按时间间隔评估心率 在咬伤事件之前、期间和之后，并比较了这些 心率值与基线心率显着 与之前和之前的间隔相比，在咬人事件期间升高 咬后间隔内心率已经开始增加 与咬之前相比，明显升高表明 基线 咬人后，心率立即急剧下降至 根据预期的基线水平 张力降低假说 排除简单的运动解释 为了观察心率的变化，我们检查了类似的活动（咬 背心）并进行相同的心率分析 与心率适度的、非显着的增加有关 在接下来的时间间隔内心率几乎没有变化这些结果 表明 NIB 可以产生与张力无关的张力降低 简单的运动变化 进一步的研究将旨在检查 猴子咬人前后的应激激素水平 张力减轻假说的独立证实