THE REFINEMENT & APPLICATION OF MEDICAL DECISION MAKING IN PREVENTION SCIENCES

精致化

• 批准号: 7052538
• 负责人: Edward Michael Foster
• 金额: $ 19.71万
• 依托单位: PENNSYLVANIA STATE UNIVERSITY, THE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-03-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7052538
• 关键词: behavioral /social science research tag; decision making; drug abuse prevention; drug abuse therapy; health science research; human data; information dissemination; longitudinal human study; method development; statistics /biometry

Economic analysis of the treatment and prevention of drug use and abuse is essential for maximizing the public health benefit of expenditures on those interventions and treatments. The tools of medical decision making and statistical decision theory are potentially quite useful in research on drug use and abuse but have not been utilized. The overarching goal of this application is to tailor and apply those tools to the treatment and prevention of drug use and abuse. This project has two specific aims: 1. To develop MDM models for three substantive areas of importance to the prevention and treatment of drug use and abuse: (a) the treatment of attention deficit disorders, which are frequently comorbid with drug use; (b) screening and treatment of young children at risk for drug use and abuse and of other long-term behavior problems; and (c) the use of drug courts for juvenile offenders. For each area of application, we will (i) specify a MDM model linking the problems to proximal outcomes that shape key long-term outcomes for children; (ii) draw on relevant literature and expert opinion to develop estimates of the parameters of those models; (iii) model the cost-effectiveness of alternative treatments; and (iv) use a value of information analysis (VOI) to prioritize future research. 2. To encourage the use of these methods among substance use and abuse researchers through peer-reviewed journals in the field; relevant conferences; training activities for and consultation with other researchers and the center's web site. This work will focus not only on disseminating the substantive findings of our models but also on making the technical tools on which they are based more widely accessible to applied researchers.

对药物使用和滥用的治疗和预防的经济分析对于最大程度地利用了这些干预措施和治疗的支出的公共卫生益处。医疗决策和统计决策理论的工具在对药物使用和滥用的研究中可能非常有用，但尚未使用。该应用程序的总体目标是量身定制和应用这些工具，以治疗和预防吸毒和滥用。该项目具有两个具体的目的：1。为预防和治疗药物使用和滥用的三个重要领域开发MDM模型：（a）治疗注意力不足障碍，这些疾病经常与吸毒合并症； （b）筛选和 治疗有吸毒和滥用毒品和其他长期行为问题的幼儿； （c）为少年罪犯使用毒品法庭。对于每个应用领域，我们将（i）指定一个MDM模型，该模型将问题与近端结果联系起来，以塑造儿童的重要长期结果； （ii）利用相关文献和专家意见来制定这些模型参数的估计； （iii）对替代治疗的成本效益进行建模； （iv）使用信息分析的价值（VOI）来确定未来的研究。 2。鼓励通过该领域的同行评审期刊在药物使用和滥用研究人员中使用这些方法；相关会议；培训活动和咨询 其他研究人员和中心的网站。这项工作不仅将着重于传播我们的模型的实质发现，而且还致力于制造其基于应用研究人员更广泛访问的技术工具。