Eastern Cooperative Oncology Group

东部肿瘤合作组

• 批准号: 6919271
• 负责人: JOHN K ERBAN
• 金额: $ 32.47万
• 依托单位: TUFTS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1982
• 资助国家: 美国
• 起止时间: 1982-12-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6919271
• 关键词: AIDS; Asians; antineoplastics; biological response modifiers; blood /lymphatic neoplasm; bone marrow transplantation; brain neoplasms; breast neoplasms; cancer prevention; clinical research; clinical trials; combination cancer therapy; combination chemotherapy; cooperative study; fluorescent in situ hybridization; gastrointestinal neoplasms; gene therapy; head /neck neoplasm; health behavior; health science research potential; human subject; human therapy evaluation; leukemia; lymphoma; medically underserved population; melanoma; minimal residual disease; multiple myeloma; neoplasm /cancer chemotherapy; neoplasm /cancer genetics; neoplasm /cancer immunotherapy; neoplasm /cancer pharmacology; neoplasm /cancer radiation therapy; neoplasm /cancer surgery; neoplasm /cancer vaccine; nucleic acid sequence; pathology; patient care management; patient oriented research; prognosis; reproductive system neoplasm; sign /symptom; thorax neoplasm; tissue resource /registry; urinary tract neoplasms

DESCRIPTION (provided by applicant): Tufts-New England Medical Center (Tufts-NEMC) has served as a main institution for the Eastern Cooperative Oncology Group for 40 years. During that time, the network has enrolled over 6500 patients on NCI sponsored cancer clinical trials and it has made many scientific and administrative contributions to ECOG. The development of a large and growing network throughout New England, combined with contributions to scientific programs in bone marrow transplantation, leukemia, lymphoma, breast cancer, and symptom management have distinguished the Tufts-New England Medical Center's contributions to ECOG over these years. This grant requests support for Tufts-NEMC to continue its mission as a main ECOG institution, supporting NCI sponsored cancer clinical trials throughout New England. The grant will support scientific activity, growth in accrual, and importantly, continued mentoring of promising junior investigators. The Tufts-NEMC ECOG network includes a large network of hospitals in 3 New England States: Massachusetts, Connecticut, and Maine, in addition to obligations in Rhode Island. We request salary support for the Principal Investigator, scientific study chairs, data managers and coordinators to support these efforts. Increasingly, network support requires emphasis on regulatory compliance, auditing and implementation of electronic tools for registration and data submission. Funds will support the Principal Investigator, study chairs, data management, and travel to and from ECOG meetings and shall be used to enhance electronic communications and data management across a broad geographic region. New affiliate sites have successfully opened since the last grant, and improving accrual and implementation of standardized network data monitoring are important goals for this next 5 year grant. A new research program in symptom management will be initiated. Mentoring successful junior scientists and introduction of postdoctoral fellows and junior faculty to ECOG to increase accrual and related scientific activities are important aspects of this program for the next 5 years.

描述（由申请人提供）：塔夫茨新英格兰医学中心（Tufts-Nemc）已在东部合作肿瘤学集团担任主要机构已有40年了。 在此期间，该网络已招募了6500多名NCI赞助的癌症临床试验，并为ECOG做出了许多科学和行政贡献。 整个新英格兰的大型网络的发展，再加上对骨髓移植，白血病，淋巴瘤，乳腺癌和症状管理的科学计划的贡献，使塔夫茨新英格兰医疗中心对ECOG的贡献区分开来。 该赠款要求支持Tufts-Nemc继续作为主要ECOG机构的任务，并支持NCI赞助的整个新英格兰的癌症临床试验。 该赠款将支持科学活动，应计增长，重要的是，继续指导有前途的初级研究人员。 Tufts-NEMC ECOG网络包括在新英格兰3个州的大型医院网络：马萨诸塞州，康涅狄格州和缅因州，除了在罗德岛州的义务外。 我们要求为主要研究人员，科学研究椅，数据经理和协调员提供薪水支持，以支持这些努力。 越来越多的网络支持需要强调监管合规性，审计和实施电子工具进行注册和数据提交。 资金将支持主要研究人员，研究椅，数据管理以及往返ECOG会议的旅行，并应用于增强广泛地理区域的电子通信和数据管理。 自上次赠款以来，新的会员站点已成功开放，改善应计和标准化网络数据监控的实施是下一5年赠款的重要目标。 将启动一项新的症状管理研究计划。 指导成功的初级科学家，并将博士后研究员和初级教师引入ECOG，以增加应计和相关的科学活动，这是未来5年计划的重要方面。