Method for Glaucoma Screening in Primary Care Offices

初级保健办公室青光眼筛查方法

• 批准号: 6854066
• 负责人: RAN C. ZEIMER
• 金额: $ 36.53万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-02-01 至 2008-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6854066
• 关键词: bioengineering /biomedical engineering; bioimaging /biomedical imaging; biomedical equipment development; clinical research; diagnosis design /evaluation; diagnosis quality /standard; digital imaging; eye disorder diagnosis; glaucoma; human middle age (35-64); human old age (65+); human subject; managed care; method development; primary care physician; stereophotography

The purpose of this project is to develop a screening device and methodology for detection of glaucoma in the office of primary physicians. Glaucoma is a major source of vision loss in this country. Treatment of glaucoma can prevent vision loss; however, approximately half of those who have glaucoma are not receiving treatment because they are unaware of their condition. Efforts to encourage and facilitate routine checkups by ophthalmologists have had little success, even when offered free of charge. The DigiScope is a screening system successfully in use in primary care physicians' offices for the detection of diabetic retinopathy. It is proposed to upgrade the capabilities of the DigiScope to perform screening of glaucoma. The principal improvement to the DigiScope necessary to produce a viable glaucoma screening device is to add stereoscopic imaging capability through pupils that have not been dilated pharmacologically. The study encompasses specific aims: development and technical evaluation of non-mydriatic stereo imaging capability of the DigiScope; comparison of the capability of the non-mydriatic DigiScope to detect glaucomatous damage to that of the 'gold standard' conventional mydriatic color stereophotography in a pilot study; evaluation of the practicality of the non-mydriatic stereo DigiScope in a primary care setting; and, development of processing and display tools to examine DigiScope stereo images at a reading center. Formal and independent validation tests will be needed after the completion of this proposal. Should screening with the DigiScope pass such tests, it will allow many individuals to benefit from treatment and reduce their risk of losing vision.

该项目的目的是开发一种用于初级医生办公室青光眼检测的筛查设备和方法。青光眼是这个国家视力丧失的主要原因。治疗青光眼可以预防视力丧失；然而，大约一半的青光眼患者没有接受治疗，因为他们不知道自己的病情。鼓励和便利眼科医生进行例行检查的努力收效甚微，即使是免费提供。 DigiScope 是一种筛查系统，已在初级保健医生办公室成功使用，用于检测糖尿病视网膜病变。建议升级 DigiScope 的青光眼筛查能力。生产可行的青光眼筛查设备所需的 DigiScope 的主要改进是 通过未药理学扩张的瞳孔增加立体成像能力。该研究包含具体目标：DigiScope 免散瞳立体成像能力的开发和技术评估；在一项试点研究中，将免散瞳 DigiScope 检测青光眼损伤的能力与“黄金标准”传统散瞳彩色立体摄影的能力进行比较；评估免散瞳立体 DigiScope 在初级保健环境中的实用性；开发处理和显示工具，以在阅读中心检查 DigiScope 立体图像。该提案完成后将需要进行正式和独立的验证测试。 如果 DigiScope 筛查通过此类测试，将使许多人受益于治疗并降低失去视力的风险。