Method for Glaucoma Screening in Primary Care Offices

初级保健办公室青光眼筛查方法

• 批准号: 6854066
• 负责人: RAN C. ZEIMER
• 金额: $ 36.53万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-02-01 至 2008-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6854066
• 关键词: bioengineering /biomedical engineering; bioimaging /biomedical imaging; biomedical equipment development; clinical research; diagnosis design /evaluation; diagnosis quality /standard; digital imaging; eye disorder diagnosis; glaucoma; human middle age (35-64); human old age (65+); human subject; managed care; method development; primary care physician; stereophotography

The purpose of this project is to develop a screening device and methodology for detection of glaucoma in the office of primary physicians. Glaucoma is a major source of vision loss in this country. Treatment of glaucoma can prevent vision loss; however, approximately half of those who have glaucoma are not receiving treatment because they are unaware of their condition. Efforts to encourage and facilitate routine checkups by ophthalmologists have had little success, even when offered free of charge. The DigiScope is a screening system successfully in use in primary care physicians' offices for the detection of diabetic retinopathy. It is proposed to upgrade the capabilities of the DigiScope to perform screening of glaucoma. The principal improvement to the DigiScope necessary to produce a viable glaucoma screening device is to add stereoscopic imaging capability through pupils that have not been dilated pharmacologically. The study encompasses specific aims: development and technical evaluation of non-mydriatic stereo imaging capability of the DigiScope; comparison of the capability of the non-mydriatic DigiScope to detect glaucomatous damage to that of the 'gold standard' conventional mydriatic color stereophotography in a pilot study; evaluation of the practicality of the non-mydriatic stereo DigiScope in a primary care setting; and, development of processing and display tools to examine DigiScope stereo images at a reading center. Formal and independent validation tests will be needed after the completion of this proposal. Should screening with the DigiScope pass such tests, it will allow many individuals to benefit from treatment and reduce their risk of losing vision.

该项目的目的是开发一种筛查装置和方法，用于在小学医师办公室中检测青光眼。青光眼是该国视力丧失的主要来源。青光眼的治疗可以预防视力丧失；但是，大约一半的具有青光眼的人没有接受治疗，因为他们没有意识到自己的状况。即使免费提供，眼科医生鼓励和促进常规检查的努力也没有成功。 Digiscope是成功用于初级保健医师办公室的筛查系统，用于检测糖尿病性视网膜病。提议升级Digiscope进行青光眼筛查的能力。生产可行的青光眼筛查装置所需的Digiscope的主要改进是 通过尚未在药理上扩张的学生添加立体成像能力。该研究涵盖了特定的目的：Digiscope的非毛利亚立体影像能力的开发和技术评估；在一项试验研究中，非肌二虫挖掘机能够检测到“金标准”常规的肌动物立体观念的能力的能力比较；在初级保健环境中评估非肌动式立体声Digiscope的实用性；并且，开发处理和展示工具以检查阅读中心的Digiscope立体声图像。该提案完成后需要进行正式和独立的验证测试。 如果通过Digiscope进行筛查，则将允许许多人从治疗中受益并降低视力的风险。