Improving Battery Performance for Cardiac Pacing

提高心脏起搏的电池性能

• 批准号: 6992283
• 负责人: JEFFREY T DEAL
• 金额: $ 21.34万
• 依托单位: GENTCORP LIMITED
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2006-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6992283
• 关键词: biomaterial development /preparation; biomaterial evaluation; biomedical device power system; biotechnology; clinical biomedical equipment; electronic pacemaker; electrostimulus; energy source; heart function; heart prosthesis; implantable defibrillators; lithium; medical implant science; miniature biomedical equipment

DESCRIPTION (provided by applicant): Implantable cardioverter defibrillators (ICDs) require high-reliability power sources that provide long device life and a short, consistent capacitor charge time. Both of these performance parameters can be improved by optimizing battery performance. By increasing the life of the ICD, patients will require fewer replacement surgeries, lowering the lifetime cost of therapy for the patient. Predictably consistent performance of the power source is highly desirable. ICDs marketed by Medtronic, St. Jude, and Guidant all use lithium silver vanadium oxide (SVO) battery chemistries and all display a significant increase in charge time, in some cases up to 500%, as the battery is depleted. There have been cases with some device models where charge times become unacceptably long before the battery reaches the elective replacement indicator (ERI) voltage. Fast charge time is of clinical importance, and a delay in the delivery of the shock has negative physiologic effects. Presently no battery system fully provides all the performance characteristics desired by clinicians at relatively low cost. The research will focus on the development of a high-performance rechargeable lithium battery that will be used in conjunction with a primary lithium cell to provide a hybrid battery system. This hybrid combination of two distinct battery systems has demonstrated superior performance in a defibrillator application and the development of a rechargeable lithium battery with high energy density and low self-discharge will provide a high-performance, low-cost alternative power source for implantable medical devices with medium-to-high energy requirements. The major aim of the research is to identify and evaluate the state of rechargeable lithium battery technology, identify and procure the best candidate materials and processes needed to produce suitable cells, develop the hybrid battery design and develop the tools to evaluate battery performance.

描述（由申请人提供）： 植入式心脏复律除颤器 (ICD) 需要高可靠性电源，以提供较长的设备使用寿命和较短且一致的电容器充电时间。这两个性能参数都可以通过优化电池性能来提高。通过延长 ICD 的使用寿命，患者将需要更少的更换手术，从而降低患者的终生治疗成本。非常需要电源具有可预测的一致性能。 Medtronic、St. Jude 和 Guidant 销售的 ICD 均使用锂银钒氧化物 (SVO) 电池化学物质，并且随着电池耗尽，充电时间均显着增加，在某些情况下高达 500%。在某些情况下，某些设备型号在电池达到选择性更换指示 (ERI) 电压之前，充电时间会变得令人无法接受。快速充电时间具有临床重要性，而电击传递的延迟会产生负面的生理影响。目前还没有电池系统能够以相对较低的成本完全提供临床医生所需的所有性能特征。 该研究将重点开发高性能可充电锂电池，该电池将与一次锂电池结合使用以提供混合电池系统。这种两种不同电池系统的混合组合已在除颤器应用中表现出卓越的性能，并且开发具有高能量密度和低自放电的可充电锂电池将为植入式医疗设备提供高性能、低成本的替代电源具有中到高的能量需求。该研究的主要目的是确定和评估可充电锂电池技术的状态，确定和采购生产合适电池所需的最佳候选材料和工艺，开发混合电池设计并开发评估电池性能的工具。