Improving Battery Performance for Cardiac Pacing

提高心脏起搏的电池性能

• 批准号: 6992283
• 负责人: JEFFREY T DEAL
• 金额: $ 21.34万
• 依托单位: GENTCORP LIMITED
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2006-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6992283
• 关键词: biomaterial development /preparation; biomaterial evaluation; biomedical device power system; biotechnology; clinical biomedical equipment; electronic pacemaker; electrostimulus; energy source; heart function; heart prosthesis; implantable defibrillators; lithium; medical implant science; miniature biomedical equipment

DESCRIPTION (provided by applicant): Implantable cardioverter defibrillators (ICDs) require high-reliability power sources that provide long device life and a short, consistent capacitor charge time. Both of these performance parameters can be improved by optimizing battery performance. By increasing the life of the ICD, patients will require fewer replacement surgeries, lowering the lifetime cost of therapy for the patient. Predictably consistent performance of the power source is highly desirable. ICDs marketed by Medtronic, St. Jude, and Guidant all use lithium silver vanadium oxide (SVO) battery chemistries and all display a significant increase in charge time, in some cases up to 500%, as the battery is depleted. There have been cases with some device models where charge times become unacceptably long before the battery reaches the elective replacement indicator (ERI) voltage. Fast charge time is of clinical importance, and a delay in the delivery of the shock has negative physiologic effects. Presently no battery system fully provides all the performance characteristics desired by clinicians at relatively low cost. The research will focus on the development of a high-performance rechargeable lithium battery that will be used in conjunction with a primary lithium cell to provide a hybrid battery system. This hybrid combination of two distinct battery systems has demonstrated superior performance in a defibrillator application and the development of a rechargeable lithium battery with high energy density and low self-discharge will provide a high-performance, low-cost alternative power source for implantable medical devices with medium-to-high energy requirements. The major aim of the research is to identify and evaluate the state of rechargeable lithium battery technology, identify and procure the best candidate materials and processes needed to produce suitable cells, develop the hybrid battery design and develop the tools to evaluate battery performance.

描述（由申请人提供）： 可植入的心脏逆转除颤器（ICD）需要高可靠性的功率来源，这些功率源可提供长时间的设备寿命和短，一致的电容器充电时间。这两个性能参数都可以通过优化电池性能来改进。通过延长ICD的寿命，患者将需要更少的替换手术，从而降低患者的终身治疗成本。可以预见的是，电源的性能是非常可取的。 ICD由Medtronic，St.Jude和Guidant销售的ICD都使用锂银氧化锂（SVO）电池化学分配，并且所有电池的充电时间大幅增加，在某些情况下，由于电池耗尽，因此最高可达500％。在某些设备模型的情况下，充电时间在电池达到选择性替换指示器（ERI）电压之前就变得无法接受。快速充电时间具有临床重要性，冲击的延迟会产生负面的生理影响。目前，没有电池系统完全以相对较低的成本提供临床医生所需的所有性能特征。 这项研究将重点放在开发高性能可充电锂电池上，该电池将与原代锂电池一起使用，以提供混合电池系统。这种两个不同电池系统的混合组合在除颤器应用中表现出了出色的性能，并且具有高能量密度和低自我电荷的可充电锂电池的开发将为具有中等至高能需求的植入式医疗设备提供高性能，低成本的替代电源。该研究的主要目的是识别和评估可充电锂电池技术的状态，识别和采购生产合适细胞所需的最佳候选材料和过程，开发混合电池设计并开发用于评估电池性能的工具。