Core--Biostatistics facility

核心--生物统计设施

• 批准号: 7055207
• 负责人: JAMES J SCHLESSELMAN
• 金额: $ 9.75万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7055207
• 关键词: biomedical facility; cooperative study; drug design /synthesis /production; radioprotective agents; statistical service /center; statistics /biometry

The Biostatistics Core will contribute statistical expertise to the development of efficient dose-finding designs to assess in vitro and in vivo toxicity and efficacy of novel small-molecule radiation protective and mitigator agents used individually and in combination; perform statistical analyses of data from key experiments in vitro and in vivo; work with the Project and Core investigators, to ensure that data collection and database development are appropriate for the requisite statistical analyses; contribute to the review of pilot-project proposals and provide statistical support to those that are funded by this CMCR; and collaborate with investigators in writing and preparing progress reports, abstracts, manuscripts, and presentations.

生物统计学核心将为开发有效的剂量调查设计促进统计专业知识，以评估新型小分子辐射保护和减轻剂的体外毒性和体内毒性以及单独和组合使用的缓解剂的功效；从体外和体内进行关键实验的数据进行统计分析；与项目和核心调查人员合作，以确保数据收集和数据库开发适合必要的统计分析；为审查试点项目的提案做出贡献，并向该CMCR资助的人提供统计支持；并与调查人员合作写作和准备进度报告，摘要，手稿和演示文稿。