Opioid medications without prescriptions on the internet

互联网上没有处方的阿片类药物

• 批准号: 6956049
• 负责人: DOUGLAS B. MARLOWE
• 金额: $ 23.55万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2007-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6956049
• 关键词: Internet; adult human (21+); age difference; behavioral /social science research tag; clinical research; codeine; community health services; data collection methodology /evaluation; drug abuse information system; drug controls; high risk behavior /lifestyle; human data; longitudinal human study; methadone; method development; narcotics; questionnaires; self medication; substance abuse epidemiology; substance abuse related behavior; time resolved data

DESCRIPTION (provided by applicant): Several national drug use monitoring studies have reported increases in the use of prescription opioids, particularly among young people. Although the factors causing this increase in prescription opioid use are unknown, the leadership of the National Institute on Drug Abuse (NIDA), and the White House Office of National Drug Control Policy (ONDCP) have expressed concerns that online pharmacies selling medications without a prescription may be playing a role. No prescription websites (NPWs) advertise to sell prescription medications over the internet without a legal prescription. A study published June 17, 2004 by the U.S. General Accounting Office (GAO) found that 10 out of the 11 websites (91 percent) from whom opioid medications were purchased without a prescription delivered the medications as advertised. NPWs remove healthcare professionals from the prescription process increasing the risk for drug misuse, abuse, dependence, and overdose. Of particular concern is the role NPWs might play in initiating opioid use among young people; individuals under 21 years of age are the most frequent users of the internet, and are in the age group where drug use typically begins. Almost nothing is known about the availability of NPWs, or their characteristics, or the people who use them. The development of reliable NPW monitoring methods, the development of basic knowledge about NPWs, and the assessment of their role in un-prescribed opioid use, are critical first steps in developing a public health response to this internet-borne vector for substance abuse. To begin developing this basic knowledge about NPWs and their role in prescription opioid use, this proposal has the following specific aims: 1. Expand the investigators ongoing Opioid NPW monitoring studies by including multiple opioid medication search terms and establishing the reliability of these website monitoring methods; 2. Maintain an expanded Opioid NPW Database with descriptive data on all NPWs identified and archived webpages; 3. Examine the effect of age and change over time in the prevalence of internet purchases for prescription opioids by adding a question about how medications were obtained to an ongoing multi-site, community-based clinical information system; 4. Explore the prevalence of internet purchases in two prescription opioid-using samples by adding a question about how medications were obtained to two ongoing opioid diversion surveillance studies.

描述（由申请人提供）：几项国家药物使用监测研究报告说，处方阿片类药物的使用增加，尤其是在年轻人中。尽管导致处方阿片类药物使用增加的因素尚不清楚，但国家药物滥用研究所（NIDA）和白宫国家药物控制政策（ONDCP）的领导层表示担心在线药房出售无处方药的药物可能会起着作用。没有处方网站（NPWS）在没有法律处方的情况下通过互联网销售处方药做广告。 2004年6月17日发表的一项研究由美国一般会计办公室（GAO）发表，发现在没有处方的11个网站（91％）中，有10个网站（91％），从中购买了阿片类药物。 NPWS从处方过程中删除医疗保健专业人员，从而增加了滥用毒品，滥用，依赖和过量的风险。特别关心的是，NPW在年轻人中启动阿片类药物使用中可能扮演的角色； 21岁以下的个人是互联网上最常见的使用者，并且是使用药物使用通常开始的年龄组。关于NPW，其特征或使用它们的人的可用性几乎一无所知。开发可靠的NPW监测方法，有关NPW的基本知识的发展以及评估其在非处方阿片类药物使用中的作用，这是对对这种滥用药物滥用的互联网传播媒介产生公共卫生响应的关键第一步。为了开始发展有关NPW及其在处方阿片类药物使用中的作用的基本知识，该提案具有以下具体目的：1。通过包括多种阿片类药物搜索术语并确定这些网站监控方法的可靠性，扩大研究人员正在进行的阿片类药物NPW监测研究； 2。维护一个扩展的阿片类NPW数据库，并在所有已识别和存档的网页上使用描述性数据； 3。通过添加有关如何在正在进行的多站点，基于社区的临床信息系统中获得药物的问题，检查处方阿片类药物的年龄和随着时间的变化的影响； 4。通过添加有关如何在两项正在进行的阿片类药物转移监测研究中获得药物的问题，探索两种处方阿片类药物样本中的互联网购买率。