Strategies for Engineered Negligible Senescence, 2nd Conference

工程可忽略衰老的策略，第二次会议

• 批准号: 7000509
• 负责人: AUBREY D DE GREY
• 金额: $ 2.5万
• 依托单位: METHUSELAH FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7000509
• 关键词: aging; cell senescence; gene therapy; meeting /conference /symposium; stem cell transplantation; tissue engineering

DESCRIPTION (provided by applicant): This conference will take place on September 7th through 11th 2005 at Queens' College, University of Cambridge, Cambridge, England. The participants will mainly be research scientists but are expected to include interested laypeople as well. The topics to be covered include a wide range of biomedical and biotechnological disciplines relevant to the eventual repair of age-related molecular and cellular damage in mammals, including stem cell therapy, nuclear transfer, somatic gene therapy and tissue engineering. The meeting will also cover innovative ways in which such technologies may be employed in the foreseeable future in the repair or obviation of age-related changed currently immutable or only modestly retardable by known interventions, such as mitochondria! mutations, lysosomal and extracellular aggregates, protein-protein crosslinks, sarcopenia, visceral adiposity and tumors. This combination of topics is not adequately combined in other conferences, but it is an essential mix for those concerned with the long-term prospects for major intervention in the aging process, which (as all gerontologists know) is the single biggest contributor to frailty and debilitation throughout the developed world. In demonstration of this, the precursor of this conference (held at the same venue in September 2003) was exceptionally successful. The upcoming meeting has been able to build on the reputation of the 2003 meeting and has already attracted a host of illustrious confirmed speakers.

描述（由申请人提供）： 本次会议将于 2005 年 9 月 7 日至 11 日在英国剑桥剑桥大学皇后学院举行。参与者主要是研究科学家，但预计也包括感兴趣的外行人士。涵盖的主题包括与最终修复哺乳动物中与年龄相关的分子和细胞损伤相关的广泛生物医学和生物技术学科，包括干细胞治疗、核移植、体细胞基因治疗和组织工程。会议还将讨论创新方式，在可预见的未来，这些技术可以用于修复或消除与年龄相关的变化，这些变化目前是不可改变的，或者只能通过已知的干预措施（例如线粒体）适度延缓！突变、溶酶体和细胞外聚集、蛋白质-蛋白质交联、肌肉减少症、内脏肥胖和肿瘤。这种主题组合在其他会议中并未得到充分结合，但对于那些关注对衰老过程进行重大干预的长期前景的人来说，这是一个必不可少的组合，因为衰老过程（正如所有老年学家都知道的那样）是导致虚弱和衰老的最大因素。整个发达国家都在衰弱。本次会议的前身（2003 年 9 月在同一地点举行）非常成功，就证明了这一点。即将召开的会议在 2003 年会议的声誉基础上再接再厉，并已吸引了众多知名人士出席演讲。