NHLBI Respiration Biology Research Training Grant

NHLBI 呼吸生物学研究培训补助金

• 批准号: 6914211
• 负责人: ANDREW H LIMPER
• 金额: $ 25.69万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6914211
• 关键词: NHLBI; Respiration; Biology; Research; Training

DESCRIPTION (provided by applicant): Respiratory diseases remain a major cause of death and disability. Training in respiratory biology will prepare young investigators for careers directed at eliminating these major causes of morbidity and mortality. This program provides intensive research training for physicians or Ph.D.s to prepare for careers as independent investigators. Over the past funding period, we have utilized the strong combined research training expertise of the Mayo Clinic Rochester, MN and Mayo Clinic Scottsdale, AZ. Dr. Andrew H. Limper, director of the Thoracic Research Unit at Mayo Rochester, will continue as program director, while Dr. James J. Lee, director of asthma research and the transgenic program at the Johnson Research Center at Mayo Scottsdale, will act as co-director. This training program arises as a natural extension of our integrated research and administrative structure. Well-developed and competitively funded research teams are present at both campuses. Faculty members hold academic appointments in the Departments of Medicine, Biochemistry/Molecular Biology, Immunology, and Physiology. Utilizing our satellite-based communication, major conferences are teleconferenced between campuses. In addition, faculty routinely travel between sites for educational, scientific, and administrative duties. Immediate communication occurs via our integrated paging and telephone systems, video links, and electronic mail. Dr. Limper and the Mayo Graduate School have considerable experience in supervising trainees as they train between Mayo sites. We propose 18 senior and 6 associate faculty members, with the research faculty being divided between the sites. Available research topics range from the biology of host defense and pulmonary infections, asthma and obstructive lung disease, extracellular matrix and lung fibrosis, the molecular basis of cystic fibrosis, transgenic animal models of disease, lung inflammation, cellular biomechanics, and protease and lipid biochemistry. We propose outstanding research opportunities for four trainee positions per year. Qualified candidates with M.D., Ph.D., or M.D., Ph.D. backgrounds are considered. We have already had significant success in the recruitment of under-represented minorities and will continue these efforts. Candidate are committed to a minimum of two, but preferably three or more years of full time research. A wide range of didactic courses is available to complement the intensive laboratory experience.

描述（由申请人提供）： 呼吸系统疾病仍然是死亡和残疾的主要原因。 呼吸生物学培训将为年轻研究人员做好旨在消除这些发病率和死亡率主要原因的职业生涯的准备。 该计划为医生或博士提供强化研究培训，为独立研究人员的职业生涯做好准备。 在过去的资助期间，我们利用了明尼苏达州罗彻斯特梅奥诊所和亚利桑那州斯科茨代尔梅奥诊所强大的综合研究培训专业知识。 梅奥罗切斯特胸科研究室主任 Andrew H. Limper 博士将继续担任项目主任，而梅奥斯科茨代尔约翰逊研究中心哮喘研究和转基因项目主任 James J. Lee 博士将代理项目主任职务。作为联合导演。 该培训计划是我们综合研究和管理结构的自然延伸。 两个校区均拥有发展完善且资金有竞争力的研究团队。 教职员工在医学、生物化学/分子生物学、免疫学和生理学系担任学术职务。利用我们的卫星通信，重大会议在校园之间进行电话会议。 此外，教师还经常在不同地点之间出差，以履行教育、科学和行政职责。 通过我们的集成寻呼和电话系统、视频链接和电子邮件进行即时通信。 Limper 博士和梅奥研究生院在监督学员在梅奥工厂之间进行培训方面拥有丰富的经验。 我们拟聘 18 名高级教职人员和 6 名副教职人员，研究人员分布在各个地点。 可用的研究主题包括宿主防御和肺部感染的生物学、哮喘和阻塞性肺病、细胞外基质和肺纤维化、囊性纤维化的分子基础、疾病的转基因动物模型、肺部炎症、细胞生物力学以及蛋白酶和脂质生物化学。 我们每年为四个实习生职位提供出色的研究机会。 具有医学博士、博士学位或医学博士、博士学位的合格候选人背景被考虑。 我们在招募代表性不足的少数群体方面已经取得了重大成功，并将继续努力。候选人致力于至少两年，但最好是三年或更长时间的全职研究。 提供广泛的教学课程来补充密集的实验室经验。