CORE--BIOINFORMATICS

核心--生物信息学

• 批准号: 7554010
• 负责人: Dale Hunter
• 金额: $ 12.66万
• 依托单位: TUFTS UNIVERSITY BOSTON
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7554010
• 关键词: biomedical facility; computer data analysis; gene expression; informatics; microarray technology; neurosciences; statistics /biometry; biomedical facility; computer data analysis; gene expression; informatics; microarray technology; neurosciences; statistics /biometry

This Core will provide Neuroscience investigators the statistical and bioinformatics tools required for the analysis of gene expression data. This Core takes advantage of the existing recently established T-NEMC Expression Array Core, that creates and analyses DNA arrays. Dr. Dale Hunter, who currently oversees the T-NEMC Expression Array Core, will direct this Core. The personnel for the Core consist of Dr. Wollenberg a bioinformatics expert (10% effort), and a to be hired bioinformatics technician (100%). In addition, the Core will purchase licenses for a sophisticated commercial software package, GeneSpring, ideal for analysis of scanned expression array image data and subsequent data mining. The addition of the Bioinformatics Core to the services provided by TEAC will allow NINDS funded investigators to receive a reduced fee structure for gene array core services.

该核心将为神经科学研究者提供分析基因表达数据所需的统计和生物信息学工具。该核心利用了现有的最近建立的T-NEMC表达阵列核心，从而创建和分析DNA阵列。目前负责T-NEMC表达阵列核心的Dale Hunter博士将指导此核心。核心人员由Wollenberg博士组成生物信息学专家（10％的努力）和A雇用生物信息学技术人员（100％）。此外，核心将为精致的商业软件包（Genespring）购买许可证，非常适合分析扫描 表达阵列图像数据和后续数据挖掘。在TEAC提供的服务中，将生物信息学核心添加到了NINDS资助的研究人员中获得降低的基因阵列核心服务的费用结构。