ROCKY MOUNTAIN REGIONAL CLINICAL TRIALS NODE

落基山区域临床试验节点

• 批准号: 7029121
• 负责人: Paula DeGraffenreid Riggs
• 金额: $ 142.76万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7029121
• 关键词: clinical research; clinical trials; community health services; cooperative study; drug abuse; drug abuse therapy; human subject; human therapy evaluation

In this country, more patients are treated for alcohol and drug abuse by community-based treatment programs than by any other provider. While community treatment programs (CTPs) have a long history of providing quality treatment to large and diverse patient populations, their treatment approaches typically are not based on the latest evidence from the scientific literature. On the other hand, scientifically tested treatments, delivered under carefully controlled situations to highly selected patient groups, may not have applicability under usual care conditions. There is an urgent need to determine if research findings obtained in resource-rich universities are valid in community-based settings. The purpose of this application is to create a Rocky Mountain Regional (RMR) Clinical Trials Node to pursue this goal. Specifically, we offer the expertise of the substance abuse researchers in the Department of Psychiatry at the University of Colorado Health Sciences Center and the treatment providers we have been affiliated with for many years. Five of these providers are committed to participating in year one of the RMR Node and five more in year two, including CTPs from the state of Utah. Our affiliated treatment providers treat a broad array of clients with substance use problems in a variety of treatment modalities. We are committed to working in true partnership with Colorado and Utah CTPs and to working collaboratively with other investigators in NIDA's Clinical Trials Network (CTN), and with officials from NIDA. We have extensive and broad experience in multi-site collaborations, including multi-site clinical trials. We have expertise in a variety of behavioral and pharmacological treatment approaches, including motivational enhancement therapy, one of the interventions the CTN will be testing in the upcoming year. Our knowledge of this intervention in motivating out-of-treatment injection drug users to enter and remain in treatment would be of great benefit to the CTN.

在这个国家，更多的患者接受了饮酒和药物滥用的治疗 基于社区的治疗计划比任何其他提供商。而社区 治疗计划（CTP）在提供高质量治疗的历史很长的历史 大型且多样化的患者人群，他们的治疗方法通常是 不是基于科学文献的最新证据。另一方面 手，经过科学测试的治疗，在精心控制的情况下进行 对高度选择的患者群体的情况，可能没有适用性 通常的护理条件。迫切需要确定是否研究 资源丰富的大学获得的发现在基于社区的 设置。该应用程序的目的是创建一座落基山 区域（RMR）临床试验节点以追求此目标。具体来说，我们提供 部门的滥用药物研究人员的专业知识 科罗拉多大学健康科学中心的精神病学和 我们隶属的治疗提供商已有很多年了。其中五个 提供者致力于参加RMR节点的第一年和五年级 第二年的更多内容，包括来自犹他州的CTP。我们的附属机构 治疗提供者用药物使用问题对待各种各样的客户 在各种治疗方式中。我们致力于真实工作 与科罗拉多州和犹他州CTPS合作，并与 NIDA临床试验网络（CTN）的其他研究人员以及官员 来自NIDA。我们在多站点合作方面拥有丰富而广泛的经验， 包括多站点临床试验。我们有各种各样的专业知识 行为和药理治疗方法，包括动机 增强疗法，CTN将在其中测试的一种干预措施之一 即将到来的一年。我们对激励这种干预的了解 进行治疗外注射吸毒者进入和继续治疗将是 对CTN有很大的好处。