Psychopathology of Compulsive Hoarding

强迫性囤积症的精神病理学

• 批准号: 6873260
• 负责人: RANDY O FROST
• 金额: $ 19.68万
• 依托单位: SMITH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6873260
• 关键词: anxiety disorders; behavioral /social science research tag; case history; clinical research; comorbidity; compulsive behavior; cooperative study; depression; disease /disorder etiology; family genetics; human subject; interview; longitudinal human study; mental health epidemiology; obsessive compulsive disorder; patient oriented research; personality disorders; psychological models; psychological tests; psychopathology; questionnaires; schizoid personality; social behavior

DESCRIPTION (provided by applicant): Compulsive hoarding is a poorly understood problem that includes excessive clutter, difficulty discarding and compulsive acquiring which are associated with considerable impairment and distress. The first phenomenological aim of this proposal (Study 1) is to study its (a) historical features and (b) relationship to other disorders, (c) to explore possible etiological features, and (d) to examine the validity of self-report measures of hoarding. The second aim (Studies 2 and 3) is to test predictions from an existing model of hoarding during laboratory studies of discarding and acquisition. Study 1 examines community and clinic samples with compulsive hoarding symptoms (n=120), clinic patients with OCD (n=120) and community controls without significant hoarding or psychiatric symptoms (n=120). Measures include standard diagnostic interviews of Axis I and II disorders, impulse control disorders, and self-report measures of hoarding symptoms, OCD, depression, and anxiety. Structured interviews for aspects of hoarding and insight, as well as pictorial, observer-rated and self-reported measures of clutter are completed in the homes of participants. Data on historical features of hoarding (e.g., age of onset, family history) will be examined in relation to hoarding symptoms and severity via logistic regression. Chi-square and logistic regression will be used to study the relationship of hoarding features to other Axis I and II condition. Exploratory analyses of possible explanatory/etiological factors in hoarding will be conducted using various statistical procedures. SEM analyses using multi-trait multi-method strategies will be used to validate self-reported hoarding symptoms against self- and observer-rated symptoms. Studies 2 and 3 will test hypothesized cognitive and affective features of hoarding through in vivo discarding and non-acquisition tasks conducted at home and in typical acquisition settings for hoarding (n=100) and community control participants (n=50) recruited from Study 1. During these tasks, participants' cognitive, emotional and behavioral responses during attempts to discard and resist acquisition will be monitored. These findings will contribute to improved understanding of emotional, behavioral and cognitive components of hoarding and their relationship to OCD and other disorders and provide a sound basis for developing treatment strategies to address this problem.

描述（由申请人提供）：强迫性ho积是一个鲜为人知的问题，其中包括过度的混乱，丢弃和强迫性获取，这与相当大的障碍和困扰有关。该提案的第一个现象学目的（研究1）是研究其（a）（a）历史特征和（b）与其他疾病的关系，（c）探索可能的病因特征，（d）研究自我报告的ho积测量的有效性。第二个目的（研究2和3）是在丢弃和获取的实验室研究期间从现有的ho积模型中测试预测。研究1研究了具有强迫性ho积症状（n = 120），强迫症患者（n = 120）的社区和诊所样本，而没有明显的ho积或精神病症状（n = 120）。措施包括轴I和II疾病的标准诊断访谈，冲动控制障碍以及ho积症状，强迫症，抑郁和焦虑的自我报告措施。在参与者的家中完成了ho积和见解方面的结构化访谈，以及绘画，观察者评价和自我报告的杂物措施。关于ho积的历史特征（例如，发病年龄，家族史）的数据将与ho积症状和严重程度有关。卡方和逻辑回归将用于研究ho积特征与其他轴I和II条件的关系。将使用各种统计程序对可能的解释/病因因素进行探索性分析。使用多特征多方法策略进行的SEM分析将用于验证自我报告的ho积症状，以防止自我和观察者评价的症状。研究2和3将测试假设的认知和情感特征，通过在家中进行的体内丢弃和非救援任务，在ho积（n = 100）（n = 100）和社区控制参与者（n = 50）中进行的典型的恢复和抗衡，在这些任务中，参与者的认知，情绪和行为均可在研究1中招募。这些发现将有助于提高人们对ho积的情绪，行为和认知成分的理解及其与强迫症和其他疾病的关系，并为制定治疗策略解决这一问题提供了可靠的基础。