Cervical Cancer Prevention in Latina Immigrants

拉丁裔移民的宫颈癌预防

• 批准号: 6966674
• 负责人: ISABEL C SCARINCI
• 金额: $ 36.46万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-15 至 2010-05-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6966674
• 关键词: Hispanic Americans; behavioral /social science research tag; cancer prevention; cervical /vaginal smear; cervix neoplasms; clinical research; clinical trials; cognitive behavior therapy; communication; culture; female; focus groups; health behavior; health education; human papillomavirus; human subject; human therapy evaluation; immigrant; longitudinal human study; mass screening; neoplasm /cancer education; personal log /diary; sex behavior; sex partner; social model; women' s health

DESCRIPTION (provided by applicant): The proposed study is a 5-year group randomized controlled trial to test the efficacy of a theory based culturally relevant intervention focusing on primary and secondary prevention of cervical cancer among Latina immigrants. We propose 4 specific aims for the present study: (1) to conduct a formative evaluation phase to develop a theory-based, culturally relevant intervention to promote primary (sexual risk education) and secondary (pap smear) prevention of cervical cancer among Latina immigrants; (2) to develop the proposed intervention based on the results of Aim 1 as well as our previous extensive qualitative and quantitative assessments in this population; (3) to implement the developed intervention among 416 Latina immigrants between the ages of 19 and 50; and (4) to evaluate the efficacy of such intervention through a group randomized trial. Although the social construction model will be the overall conceptual framework used in the present study, the PEN-3 and Health Belief Model will guide intervention development and implementation. The intervention will combine elements of the sociologic approach (which takes into account cultural beliefs, attitudes, and behaviors) and cognitive-behavioral strategies, and it will be delivered by lay health educators. The intervention group will receive both knowledge and skills training regarding primary and secondary prevention of cervical cancer, and the control group will receive education on health topics (e.g., diabetes, health care access, etc.). The study will be carried out in 2 phases. In Phase I, we will develop and refine the intervention plans and assessment tools through formative assessment. In Phase we will recruit participants, gather baseline data, randomize participants to intervention and control groups, implement and evaluate the intervention. The primary outcomes will include: (1) compliance with the U.S. Preventive Services Task Force recommendation for cervical cancer screening, i.e., Pap Smear at least every 3 years (measured through self-report and validated through medical records); and (2) increased partner communication regarding sexual behavior as well as self-efficacy (measured through self report). Secondary outcome will include: changes in knowledge, attitudes, and beliefs regarding the relationship between the human papillomavirus (HPV) infection and cervical cancer.

描述（由申请人提供）：拟议的研究是一项为期 5 年的随机对照试验，旨在测试基于理论的文化相关干预措施的有效性，重点关注拉丁裔移民宫颈癌的一级和二级预防。我们为本研究提出了 4 个具体目标：(1) 进行形成性评估阶段，以制定基于理论的、文化相关的干预措施，以促进拉丁移民中宫颈癌的初级（性风险教育）和二级（子宫颈抹片检查）预防; (2) 根据目标 1 的结果以及我们之前对该人群进行的广泛定性和定量评估，制定拟议的干预措施； (3) 对 416 名年龄在 19 岁至 50 岁之间的拉丁裔移民实施既定干预措施； (4) 通过小组随机试验评估此类干预措施的有效性。尽管社会建构模型将成为本研究中使用的总体概念框架，但 PEN-3 和健康信念模型将指导干预措施的制定和实施。干预措施将结合社会学方法（考虑文化信仰、态度和行为）和认知行为策略的要素，并将由非专业健康教育者实施。干预组将接受宫颈癌一级和二级预防的知识和技能培训，对照组将接受健康主题教育（如糖尿病、医疗保健获取等）。该研究将分两个阶段进行。第一阶段，我们将通过形成性评估来制定和完善干预计划和评估工具。在阶段中，我们将招募参与者，收集基线数据，将参与者随机分为干预组和对照组，实施和评估干预措施。主要结果将包括：(1) 遵守美国预防服务工作组关于宫颈癌筛查的建议，即至少每 3 年进行一次子宫颈抹片检查（通过自我报告进行测量并通过医疗记录进行验证）； (2) 增加伴侣关于性行为和自我效能的沟通（通过自我报告衡量）。次要结果将包括：关于人乳头瘤病毒（HPV）感染与宫颈癌之间关系的知识、态度和信念的变化。