Instruments for measuring physical activity

测量体力活动的仪器

• 批准号: 6863739
• 负责人: JAMES A LEVINE
• 金额: $ 26.77万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-03-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6863739
• 关键词: adult human (21+); bioenergetics; bioengineering /biomedical engineering; biomedical equipment development; body physical activity; body physical characteristic; body weight; calorimetry; clinical research; computational biology; computer system design /evaluation; human subject; measurement; obesity; patient oriented research; thermogenesis

DESCRIPTION (provided by applicant): The energy expended in physical activity is an important component of energy balance and body weight. Because of the variety of physical activities that free-living humans undertake, it has been extremely challenging to obtain accurate measurements of either the amount or energy cost of human physical activity. The energy expended in physical activity consists of energy expended in purposeful exercise and the energy expended in non-exercise activity thermo genesis (NEAT). The latter is even more difficult to measure than the former. Since most Americans engage in relatively little purposeful physical activity, the majority of energy expended in physical activity will be through NEAT. The research proposed in this application focuses on improving measurement systems for amount and energy cost of physical activity, with specific techniques proposed for measuring non-exercise physical activity and NEAT. We propose to develop a new high-precision Physical Activity Measurement System (PAMS). PAMS will be developed using off-the-shelf components and macros written in an universally available software program. PAMS will allow physical activity to be accurately measured at low cost and will be easily available to investigators worldwide. In Specific Aim #1, we propose to develop PAMS and validate it using subjects who will be confined in a whole-room indirect calorimeter. In Specific Aim #2, we propose to validate PAMS in free-living subjects. We will then, in Specific Aim #3, utilize PAMS to develop normative data for lean and obese subjects. In this specific aim we will define the components of NEAT in the lean and obese. This will not only be essential information for users of PAMS but will enhance our understanding of how physical activity and its components impacts obesity. PAMS has the potential to empower researchers from a variety of disciplines to measure physical activity precisely and cost-effectively. This should allow us to better define the role of physical activity in health and disease.

描述（由申请人提供）：体育锻炼中消耗的能量是能量平衡和体重的重要组成部分。由于自由生活的人类从事的体育活动种类繁多，因此获得对人类体育锻炼的数量或能源成本的准确度量或能源成本非常具有挑战性。体育锻炼中花费的能量包括在有目的的运动中花费的能量以及在非运动活性热创世纪（整洁）中花费的能量。后者比前者更难衡量。由于大多数美国人从事相对较少的有目的的体育活动，因此在体育锻炼中花费的大多数能量都是通过整洁的。 本应用程序中提出的研究重点是改善体育锻炼的数量和能源成本，并提出了用于测量非运动体育锻炼和整洁的特定技术。我们建议开发一种新的高精度体育活动测量系统（PAMS）。 PAMS将使用现成的组件和宏来开发，并在普遍可用的软件程序中编写。 PAM将允许以低成本准确地测量体育活动，并在全球调查人员中易于使用。在特定的目标＃1中，我们建议使用将被限制在整个房间间接热量计中的受试者来开发PAM并验证它。在特定的目标＃2中，我们建议在自由生活受试者中验证PAM。然后，我们将在特定的目标＃3中利用PAM来为精益和肥胖受试者开发规范性数据。在这个具体目的中，我们将定义瘦和肥胖的整洁组成部分。对于PAM的用户来说，这不仅将是必不可少的信息，而且还将增强我们对体育活动及其成分如何影响肥胖的理解。 PAM有可能使研究人员从各个学科中授权，以精确和成本效益。这应该使我们能够更好地定义身体活动在健康和疾病中的作用。