Perception and Processing of Cutaneous Stimulation

皮肤刺激的感知和处理

• 批准号: 6445420
• 负责人: ELIZABETH A Roy-Felix
• 金额: $ 3.83万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-12-15 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6445420
• 关键词: analgesia; behavioral /social science research tag; brain mapping; clinical research; foot; functional magnetic resonance imaging; heat stimulus; human subject; mechanical pressure; neural information processing; pain; perception; postdoctoral investigator; psychophysiology; skin; vibration perception

DESCRIPTION (provided by applicant): The proposed research involves the investigation of the central processing of long-duration thermal and mechanical nociceptive stimuli presented to the skin. The interaction between the systems responsible for the processing of nociceptive stimuli and of vibrotactile stimuli will also be examined. These studies will involve the combination of psychophysical measurement of sensory experience and non-invasive functional brain imaging of healthy human volunteers in order to discern where and how the brain processes information related to non-noxious and noxious skin stimulation. The ability of vibration to reduce pain will also be explored in order to assess the parameters of vibratory stimuli and the characteristics of pain that are relevant to the reduction of pain, in hopes that such results eventually lead to alternative treatment options for those suffering clinical pain.

描述（由申请人提供）：拟议的研究涉及 长时间热机械中央处理研究 伤害性刺激出现在皮肤上。系统之间的交互 负责处理伤害性刺激和振动触觉 刺激也将受到检查。这些研究将涉及结合 感官体验和非侵入性功能的心理物理测量 对健康人类志愿者进行脑部成像，以了解大脑在何处以及如何 大脑处理与无毒和有毒皮肤相关的信息 刺激。还将探讨振动减轻疼痛的能力 为了评估振动刺激的参数和特征 与减轻疼痛相关的疼痛，希望这样的结果 最终为那些患有临床症状的人带来替代治疗选择 疼痛。