Epidemiology of Traumatic Brain Injury

脑外伤的流行病学

• 批准号: 6787150
• 负责人: JEFFREY John BAZARIAN
• 金额: $ 12.1万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-24 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6787150
• 关键词: brain injury; cost effectiveness; data collection methodology /evaluation; emergency care; emergency health services; functional ability; gender difference; health care cost /financing; hospital utilization; human subject; injury prevention; interview; medical outreach /case finding; memory disorders; nervous system disorder epidemiology; outcomes research; patient /disease registry; patient oriented research; trauma; unconsciousness

DESCRIPTION (provided by applicant): A Mentored PatientOriented Research Career Development Award (K23) is proposed. The overall goal of this proposal is to give the candidate a rigorous training in research methods, such that the proposed project can be successfully completed and an independent research career be launched. The complexity and scope of the proposed project, as well as the applicant's career goals, necessitate the acquisition of sophisticated research skills. The applicant's immediate career objectives are to better understand the principles and methods of clinical research, and to apply them in an effort to set up a traumatic brain injury (TBI) surveillance system. The applicant's longterm career goals are to have established a method of TBI surveillance that can be used as a model for Monroe County, NY and the nation and better defined the epidemiology and outcome from minor TBI. A 5year, highly structured and mentored training plan is proposed. During the first 2 years, formal training leading to a degree in Masters of Public Health in Clinical Investigation at the University of Rochester Medical Center (URMC) will be undertaken. Areas to be covered include research theory, methods and ethics, with special emphasis on injury surveillance methodology. The mentor will provide instruction and guidance in the practical application of these skills, while the proposed research project is begun. During the following 3 years, the research project will be more carefully developed and implemented, data collected and proposed hypotheses tested, all under the careful guidance of the mentor. The proposed research plan, entitled "Epidemiology of Traumatic Brain Injury," is a prospective observational cohort study of all patients presenting to the Emergency Department (ED) of the URMC meeting the CDC-defined case definition of TBI. Detailed demographic and epidemiologic data, including mechanism and geographic location of injury, will be collected before exiting the ED. Outcome data will be collected via structured telephone interview on the subgroup of TBI patients who meet the study definition of minor TBI. This will permit the testing of several hypotheses related to the epidemiology and outcome from minor TBI, the determination of the most complete method of surveillance datacollection in an ED setting, and the estimation of the economic impact of minor TBI on Monroe County, NY.

描述（由申请人提供）：以患者为导向的研究生涯 拟定发展奖（K23）。该提案的总体目标是为候选人提供严格的研究方法培训，以便 拟议项目能够顺利完成并独立研究 职业生涯即将展开。拟议项目的复杂性和范围，以及 作为申请人的职业目标，有必要获得复杂的 研究技能。申请人的近期职业目标是更好地 了解临床研究的原理和方法并加以应用 努力建立创伤性脑损伤（TBI）监测系统。这 申请人的长期职业目标是建立一种 TBI 方法 可以作为纽约州门罗县和全国的典范的监控 并更好地定义了轻微 TBI 的流行病学和结果。 5年，高度 提出了结构化和指导性的培训计划。在最初的 2 年里， 获得临床公共卫生硕士学位的正式培训 罗切斯特大学医学中心 (URMC) 的调查将 进行。涵盖的领域包括研究理论、方法和伦理， 特别强调伤害监测方法。导师将 为这些技能的实际应用提供指导和指导， 同时拟议的研究项目已经开始。在接下来的3年里， 研究项目将更加仔细地制定和实施，数据 收集并测试提出的假设，所有这些都是在 导师。拟议的研究计划题为“创伤性脑的流行病学” 损伤”是一项针对所有出现损伤的患者的前瞻性观察队列研究 向 URMC 急诊科 (ED) 汇报 CDC 定义的病例 TBI 的定义。详细的人口统计和流行病学数据，包括 受伤的机制和地理位置，将在退出前收集 急诊室。结果数据将通过结构化电话访谈收集 符合轻微 TBI 研究定义的 TBI 患者亚组。这 将允许测试与流行病学相关的几个假设 轻微 TBI 的结果，确定最完整的方法 急诊室环境中的监测数据收集以及对 轻微 TBI 对纽约州门罗县的经济影响。