CORE--MORPHOLOGY

核心--形态学

• 批准号: 6717761
• 负责人: LINDA D HAZLETT
• 金额: $ 14.52万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6717761
• 关键词: autoradiography; bioimaging /biomedical imaging; biomedical facility; cryopreservation; electron microscopy; eye; immunocytochemistry; immunofluorescence technique; light microscopy; morphology; transmission electron microscopy; vision

The Morphology Module will continue to be a centralized facility in the Anatomy/Cell Biology Department that provides both light and electron microscopic expertise with priority of use to NEI funded Core vision scientists. The Module has been expanded and enhanced with Core grant, Departmental, Institutional, and individual R01 support and offers a wide range of capabilities which will not only enhance ongoing NEI funded work but which will facilitate new funding opportunities and collaborations as evidenced below. The Module contains the JEOL 1010 transmission and the 840A scanning EM. The 1900 sq. ft. Morphology Module in rooms 7341, 7350 and 7354 Scott Hall provides for light and electron microscopy, tissue processing and photography. Superb technical support to investigators continues to be provided by a skilled research assistant, Mr. Ronald Barrett. Collaboration within the Module occurs in a variety of ways. Most basically, the Module provides skilled technical expertise and well-maintained equipment to NEI funded individuals who are not primarily morphologists. For example, an ophthalmologist may need to document by morphological or photographic methods a cell population that he is interested in isolating and characterizing or growing in the Core tissue culture facility. The type of assistance provided by the Module for this need is at a simple, yet important level to that individual. Collaboration may also consist of assistance in experimental protocol development, determining appropriate fixatives to be utilized, interpretation of morphological data, photographic figure preparation and lastly, possible collaboration in manuscript submission. It is also the goal of the Module to enhance, at lower priority, collaboration and productivity of those who are seeking NEI funds by providing technical assistance, equipment availability and interaction with vision researchers of diverse fields. These types of collaborations and interactions are currently provided for by the facility and it is the goal of the Module director to continue to encourage and expand them.

形态模块将继续是解剖学/细胞生物学的集中设施 为NEI资助的核心视觉科学家提供优先使用光和电子显微镜专业知识的部门。该模块已通过核心赠款，部门，机构和个人R01支持扩展和增强，并提供了广泛的功能，不仅可以增强正在进行的NEI资助工作，而且还将促进新的资金机会和合作，如下所示。 该模块包含JEOL 1010传输和840A扫描EM。房间7341、7350和7354 Scott Hall的1900平方英尺形态模块提供了光和电子显微镜，组织加工和摄影。向调查人员提供的极好的技术支持继续由 熟练的研究助理罗纳德·巴雷特先生。 模块内的协作以多种方式进行。基本上，该模块为不主要是形态学家的Nei资助的个人提供熟练的技术专业知识和维护良好的设备。例如，眼科医生可能需要通过形态或照相方法记录他有兴趣隔离和表征或生长的细胞种群 文化设施。该模块为该需求提供的援助类型对该人来说是一个简单而重要的水平。协作还可能包括在实验协议开发方面的帮助，确定要使用的适当固定剂，形态学数据的解释，摄影人物的准备，最后是手稿提交中可能的合作。它也是该模块通过提供技术援助，设备可用性以及与各种领域的视觉研究人员的互动来提高优先级的协作和生产率的模块的目标。这些类型的合作和互动目前由该设施提供，这是模块主管继续鼓励和扩展它们的目标。