Ethics: A Bridge for Communities and Scientists

伦理：社区和科学家的桥梁

• 批准号: 6778281
• 负责人: Ann Freeman Cook
• 金额: $ 21.16万
• 依托单位: UNIVERSITY OF MONTANA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2007-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6778281
• 关键词: asbestos; behavioral /social science research tag; clinical research; education evaluation /planning; environmental exposure; ethics; gene environment interaction; health education; human subject; occupational disease /disorder; pneumoconiosis; pollution related respiratory disorder

DESCRIPTION (provided by applicant) This proposal responds to the need for a sustained dialogue that promotes public understanding of the social, ethical and legal implications of the gene-environment interactions associated with asbestos-related diseases (ARDs). It is designed to use good science to achieve good community dialogue. The health problems discussed in this narrative were created by high levels of exposure to asbestos fibers (tremolite-actinolite series) from a vermiculite mine, operated in the Libby area, in Lincoln County Montana, from the 1920s through 1991. Exposures to asbestos varied for workers and residents of the community depending on a number of factors. The investigators propose a comprehensive, collaborative and participatory, 5-year initiative that will specifically increase community understanding of the interplay between gene-environment interactions by the following means: 1) assessing community knowledge of health impacts and identifying existing gaps in public understanding of asbestos-related disease; 2) developing and implementing an electronic and on-site, culturally appropriate and accessible educational curriculum that will provide a wide array of resources that help the public understand the risks of environmentally related disease, the ethical and economic implications associated with those risks, and the strategies that protect against discrimination and psychological stress; 3) fortifying and extending the ongoing dialogue between scientists and the public by combining accurate translations of the scientific findings and community knowledge into an educational curriculum that is culturally appropriate and accessible for Libby and other communities dealing with asbestos-related diseases; and 4) assessing the impact of the educational interventions provided during the 5-year project so as to ensure that all methodologies are responsive to evolving needs and can be transplanted to other communities.

描述（由申请人提供） 该提案满足了持续对话的需要，以促进公众对与石棉相关疾病（ARD）相关的基因-环境相互作用的社会、伦理和法律影响的理解。它旨在利用良好的科学来实现良好的社区对话。 本叙述中讨论的健康问题是由于从 20 世纪 20 年代到 1991 年间大量接触来自蒙大拿州林肯县利比地区的蛭石矿的石棉纤维（透闪石-阳起石系列）而造成的。社区的工人和居民取决于多种因素。 研究人员提出了一项为期 5 年的综合性、协作性和参与性举措，将通过以下方式专门增进社区对基因与环境相互作用之间相互作用的理解：1) 评估社区对健康影响的了解并确定公众对石棉理解中存在的差距-相关疾病； 2) 开发和实施电子和现场、文化上适当且易于理解的教育课程，该课程将提供广泛的资源，帮助公众了解与环境相关的疾病的风险、与这些风险相关的伦理和经济影响，以及防止歧视和心理压力的策略； 3) 通过将科学发现和社区知识的准确翻译结合到适合利比和处理石棉相关疾病的其他社区文化上且易于理解的教育课程中，加强和扩大科学家与公众之间正在进行的对话； 4) 评估五年项目期间提供的教育干预措施的影响，以确保所有方法都能满足不断变化的需求，并可以移植到其他社区。