Bipolar Illness Intervention in Hispanic Communities

西班牙裔社区双相情感障碍干预

• 批准号: 6817706
• 负责人: CHARLES LEE BOWDEN
• 金额: $ 50.46万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-09 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6817706
• 关键词: Hispanic Americans; biomedical facility; bipolar depression; clinical research; community mental health services; health science research support; mental disorder prevention

DESCRIPTION (provided by applicant): This program seeks to establish a Developing Center for Interventions and Service Research (DCISR) that will forge an academic-community partnership to conduct interdisciplinary interventions research that will improve care of bipolar disorders, study moderators and mediators in the community that affect outcomes and participation in clinical research, and be of particular relevance to Hispanic Americans. The DCISR will enable the applicants to expand and develop their research capabilities, and contribute to greater alignment of research outcomes with community needs. With the DCISR infrastructure, the applicants will increase community involvement in study planning and management, and develop study designs better able to improve community-relevant interventions and the generalizability of results. These accomplishments will be greatly enriched by the opportunity to study in a comparative effort the Hispanic population that constitutes 55% of the population of the ninth largest city in the U.S. The DCISR brings together a multidisciplinary group of investigators with differing research foci around a central area of interventions and public health study on BD. The DCISR will develop a scale that provides an aggregate measure of psychopathology in BD, as well as sub-scale measurement of the full scope of depressive and manic symptomatology and will integrate data on clinical, treatment, neuroimaging, and genetic research in bipolar subjects into one central database. The training components of the Center will capitalize on the interdisciplinary model, with its potential for training beyond a primary focus of interest and access a broader group of mentors with relevant expertise to interventions research in BD. The scientific theme of the DCISR will be to provide a focal point for BD research in the UTHSCSA and the San Antonio area. Administration of the Center will be led by an Operations Committee that will have responsibility for the evaluation of intervention studies, linking research staff and objectives of the DCISR with the community and community stakeholders, oversight of data management and statistical operations, infrastructure development, training, program planning and insuring that the Center goals and vision are inculcated in all its activities. The committee will work to integrate the efforts of diverse faculty participating in the DCISR, meet with and solicit the input of the Community Advisory Committee, and convey the DCISR accomplishments within the Center and beyond. The OC will oversee maintenance of DCISR resources and relationships, and monitor all DCISR studies. The strategic plan of the Center emphasizes facilitating interdisciplinary investigation, forging alliances with the community, and incorporating the information learned from study of the community into modification of designs of intervention studies, recruitment efforts, and translational efforts back to community caregivers and patients with BD. These infrastructure developments will then support two developmental projects and additional pilot studies.

描述（由申请人提供）：该计划旨在建立一个干预和服务研究发展中心（DCISR），该中心将建立学术界伙伴关系，开展跨学科干预研究，从而改善双相情感障碍、研究主持人和调解员的护理影响临床研究结果和参与的社区，并且与西班牙裔美国人特别相关。 DCISR 将使申请人能够扩展和发展他们的研究能力，并有助于使研究成果与社区需求更加一致。 借助 DCISR 基础设施，申请人将增加社区对研究规划和管理的参与，并开发能够更好地改进社区相关干预措施和结果普遍性的研究设计。 通过对占美国第九大城市人口 55% 的西班牙裔人口进行比较研究的机会，这些成就将大大丰富。DCISR 汇集了围绕中心区域具有不同研究重点的多学科研究人员小组BD 的干预措施和公共卫生研究。 DCISR 将开发一个量表，提供 BD 精神病理学的总体测量，以及抑郁和躁狂症状的全部范围的分量表测量，并将双相情感障碍受试者的临床、治疗、神经影像和基因研究数据整合到一个中央数据库。 该中心的培训部分将利用跨学科模式，其培训潜力超出了主要兴趣焦点，并获得了更广泛的具有 BD 干预研究相关专业知识的导师群体。 DCISR 的科学主题是为 UTHSCSA 和圣安东尼奥地区的 BD 研究提供焦点。 该中心的行政管理将由运营委员会领导，该委员会负责评估干预研究、将研究人员和 DCISR 的目标与社区和社区利益相关者联系起来、监督数据管理和统计操作、基础设施开发、培训、计划规划并确保中心的目标和愿景被灌输到其所有活动中。 该委员会将努力整合参与 DCISR 的不同教员的努力，与社区咨询委员会会面并征求其意见，并在中心内外传达 DCISR 的成就。 OC 将监督 DCISR 资源和关系的维护，并监督所有 DCISR 研究。 该中心的战略计划强调促进跨学科调查，与社区建立联盟，并将从社区研究中获得的信息纳入干预研究设计的修改、招募工作以及将其转化为社区护理人员和双相情感障碍患者的努力。 这些基础设施开发将支持两个开发项目和其他试点研究。