Minority Predoctoral Fellowship Program

少数族裔博士前奖学金计划

• 批准号: 6829767
• 负责人: DENISE B STEINLEIN
• 金额: $ 2.92万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-16 至 2007-06-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6829767
• 关键词: Bartonella; Borrelia; Lyme disease; Peromyscus; Rickettsiales; Rickettsiales disease; Rodentias; United States; arthropod borne communicable disease; borreliosis; disease /disorder model; disease reservoirs; disease vectors; emerging infectious disease; epizootiology; laboratory rabbit; life cycle; model design /development; polymerase chain reaction; predoctoral investigator; septicemia; ticks; wild animals; zoonosis

DESCRIPTION (provided by applicant): Bartonella species are emerging zoonoses. This project examines the infection and coinfection prevalence of Bartonella species, Borrelia burgdorferi, and Anaplasma phagocytophilum, in field-captured rodents and ectoparasites in northern California. It further tries to develop a Peromyscus mouse infection model for Bartonella washoensis, Bartonella vinsonii subsp arupensis, Bartonella vinsonii subsp berkhoffi, and Bartonella henselae. Another step is taken to evaluate transmission cycles of Bartonella washoensis and Bartonella vinsonii subsp arupensis with laboratory transmission experiments involving hard ticks (Acari: Ixodidae) as vectors. Overall, results of these experiments will provide instrumental insight into Bartonella ransmission cycles.

描述（由申请人提供）：Bartonella物种是新兴的人畜共患病。该项目研究了北加州的现场捕获啮齿动物和欧无法体现，研究了Bartonella物种，Bartonella物种，Borrelia Burgdorferi和Anaplasma phapocytophilum的感染和共同感染的率。它进一步试图开发用于Bartonella washoensis，Bartonella vinsonii subsp arupensis，Bartonella vinsonii vinsonii subsp berkhoffi和Bartonella henselae的小鼠感染模型。采取了另一个步骤，以评估Bartonella washoensis和Bartonella vinsonii uspensis的传播周期，并通过实验室传输实验（涉及硬滴答（Acari：ixodidae））作为载体。总体而言，这些实验的结果将提供对Bartonella lansmission周期的工具见解。