Perceptions Of Benefits And Risks-Rakai

对收益和风险的看法-Rakai

• 批准号: 6683888
• 负责人: Christine P Grady
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6683888
• 关键词: Africa; behavioral /social science research tag; clinical research; community; ethics; health science research analysis /evaluation; human population study; human subject; interview; medically underserved population; perception; population survey; rural area

This protocol has been approved by the NIAID IRB (03-CC-NO39) This study seeks to inform deliberation and resolution of ethical issues related to biomedical research in developing countries through empirical data obtained from research participants, community members, and opinion leaders in the Rakai District in Uganda. In particular, this study will look at how people involved in research in a developing country perceive the benefits and risks to communities involved in biomedical research. The study will assess people's perceptions of the effect of research on their communities. The Rakai Project is an ongoing prospective cohort study in the Rakai District of southwestern Uganda. It has an intensive population-based HIV/STD epidemiological, behavioral, and intervention research program in 46 communities in the district. A representative sample of men and women will be drawn from communities in the Rakai District to include: 1) people who have participated in Rakai Project research?including both those who have received financial compensation for their participation and those who have not, 2) people who have never been asked to participate in research, 3) people who have declined to participate in research, and 4) people who are perceived as leaders by their communities. Men and women interviewed will come from deep rural, rural, and peri-urban communities. The primary methodology of the study is a quantitative survey administered to individuals; a secondary methodology is qualitative in-depth individual interviews and focus group discussions.

该协议已获得NIAID IRB（03-CC-NO39）的批准，该研究旨在通过从研究参与者，社区成员和乌干达Rakai地区的意见领导者获得的经验数据来为与发展中国家的生物医学研究有关的道德问题提供审议和解决。特别是，这项研究将研究发展中国家研究的人们如何看待与生物医学研究有关的社区的收益和风险。该研究将评估人们对研究对社区影响的看法。 Rakai项目是在乌干达西南部Rakai区进行的一项前瞻性队列研究。它在该地区的46个社区中具有基于人群的艾滋病毒/性病流行病学，行为和干预研究计划。 Rakai区的社区将吸引一个代表性的男女样本，其中包括：1）参加Rakai项目研究的人？包括那些因参与而获得经济赔偿的人，以及那些没有参加的经济赔偿的人，2）从未被要求参与研究的人，3）拒绝参与研究的人，以及4）参与他们的社区的人。接受采访的男人和女人将来自乡村，农村和城市周边社区。该研究的主要方法是对个人进行的定量调查。次要方法是定性的深入个人访谈和焦点小组讨论。