Core--Morphology and imaging

核心--形态学与成像

• 批准号: 6893312
• 负责人: Joey V. Barnett
• 金额: $ 21.48万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-01 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6893312
• 关键词: angiogenesis; bioimaging /biomedical imaging; biomarker; biomedical facility; coronary vessels; genetic markers; histology; immunocytochemistry; in situ hybridization; morphometry; tissue /cell preparation

The Morphology and Imaging Core is critical to the support of the studies proposed. The function of the Morphology and Imaging Core is briefly outlined in four areas: 1) To provide and process specimens for in situ hybridization and immunohistochemistry; 2) To provide a facility for imaging, data, data storage and retrieval; 3) To provide training and support for all aspects of morphological analysis; and 4) To assay selected protein and gene markers to provide a comprehensive analysis of coronary vessel development. The Morphology and Imaging Core will focus our resources to provide consistent, state-of-the-art tissue processing, imaging and analysis for each Project. The Core will also act as a mechanism to disseminate results between Projects and to develop, create and maintain a comprehensive data base for gene expressing in the developing and mature coronary vasculature. Given the reliance of each project on morphological analysis, each Project will use a significantg amount of the resources available in the Morphology and Imaging Core. The support of this Core is essential to completing the stated aims of each of the four individual projects.

形态和成像核心对于支持提出的研究至关重要。形态和成像核的功能在四个领域简要概述：1）提供和处理原位杂交和免疫组织化学的标本； 2）提供一个用于成像，数据，数据存储和检索的设施； 3）为形态分析的各个方面提供培训和支持； 4）分析选定的蛋白质和基因标记，以对冠状动脉发育进行全面分析。形态和成像核心将集中我们的资源，为每个项目提供一致，最先进的组织处理，成像和分析。核心还将充当一种在项目之间传播结果并在发展中和成熟的冠状动脉脉管系统中表达基因的全面数据库之间传播结果的机制。考虑到每个项目对形态分析的依赖，每个项目将使用大量的形态和成像核心中可用的资源。该核心的支持对于完成四个单独项目的每个项目的既定目标至关重要。