Developing a new therapy for GAD: Acceptance-based CBT

开发广泛性焦虑症的新疗法：基于接受的 CBT

• 批准号: 6621177
• 负责人: LIZABETH ROEMER
• 金额: $ 15.75万
• 依托单位: UNIVERSITY OF MASSACHUSETTS BOSTON
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-12-01 至 2004-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6621177
• 关键词: Developing; new; therapy; GAD; Acceptance

DESCRIPTION (provided by applicant): Generalized anxiety disorder (GAD) is a chronic disorder that has been associated with significant psychosocial impairment, as well as health-care utilization/cost. Further, it is a highly comorbid disorder, and has been posited to be the basic anxiety disorder, which increases vulnerability for other anxiety and mood disorders. Despite the significant health impact of this disorder, it is currently the anxiety disorder for which existing treatments have demonstrated the least effectiveness. Cognitive-behavioral treatments have demonstrated the most efficacy to date; yet studies commonly find that less than half those treated meet criteria for high end state functioning after a follow-up period, indicating that more work is needed in treatment development for this disorder. Current theory and research in the area of worry and GAD highlights the role of cognitive/experiential avoidance in this disorder, suggesting that an integrative treatment that combines elements of traditional cognitive-behavioral approaches with mindfulness/acceptance-based elements from other behavioral treatments may be particularly efficacious with this population. The current application aims to further develop and refine this integrative therapy (Behavioral Mindfulness and Action Therapy for GAD; BMAT-G), develop reliable adherence and competency ratings for the therapy, and pilot the intervention by comparing BMAT-G to a wait list control group. The first phase of the study will focus on treatment development. Thirty-two clients will be treated with this new treatment and the manual will be refined through client, therapist, investigator, and consultant feedback. At the same time, adherence and competency ratings will be developed and raters will be trained to reliably administer them. Finally, thirty-two clients with a principal diagnosis of GAD will be randomly assigned to receive the newly developed intervention, or to a 14-week waitlist condition. Therapeutic gains will be assessed in several domains: anxious and depressive symptomatology, associated features (e.g., cognitive avoidance), and quality of life. Data from this development grant will be used to prepare a large-scale treatment outcome study that explores whether the addition of acceptance-based elements incrementally improves outcomes in both symptom report and broader functioning.

描述（由申请人提供）：广义焦虑症（GAD）是 与重大的社会心理有关的慢性疾病 损害以及医疗保健利用/成本。此外，这是一个高度 合并症，并被认为是基本焦虑症， 增加了其他焦虑症和情绪障碍的脆弱性。尽管有 这种疾病的重大健康影响，目前是焦虑 现有治疗表现最少的疾病 效力。认知行为疗法表现最多 迄今为止的功效；但是研究通常发现不到一半的人接受治疗 符合随访期后高端状态功能的标准， 表明该疾病的治疗发展需要更多的工作。 当前的理论和忧虑领域的研究突出了 这种疾病中的认知/经验避免了 结合传统元素的综合处理 认知行为的方法，具有正念/接受的元素 其他行为治疗可能对此特别有效 人口。当前的申请旨在进一步开发和完善这一点 综合疗法（GAD的行为正念和行动疗法； BMAT-G），为治疗增强可靠的依从性和能力评级，以及 通过将BMAT-G与等待列表对照组进行比较来试用干预措施。这 研究的第一阶段将重点放在治疗发展上。 32 客户将接受这种新处理的治疗，手册将进行完善 通过客户，治疗师，研究人员和顾问反馈。同样 时间，依从性和能力评级将开发，评估者将是 经过培训，可以可靠地管理它们。最后，有32个客户 GAD的主要诊断将被随机分配以接收新的 开发干预措施或14周的候补条件。治疗性收益 将在几个领域进行评估：焦虑和抑郁症状学， 相关特征（例如，避免认知能力）和生活质量。来自 该开发补助金将用于准备大规模的治疗结果 研究探讨是否添加基于接受的元素的研究 逐步改善症状报告和更广泛功能的结果。