Neural Basis of Song Perception in birds

鸟类鸣叫感知的神经基础

• 批准号: 6640513
• 负责人: BRENDAN J REEVES
• 金额: $ 2.95万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2005-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6640513
• 关键词: animal communication behavior; auditory feedback; behavior test; behavioral /social science research tag; brain morphology; cAMP response element binding protein; ethology; experimental brain lesion; hearing; immunocytochemistry; long term memory; morphometry; neural information processing; neuropsychology; operant conditionings; predoctoral investigator; reinforcer; social behavior; songbirds; sound perception

DESCRIPTION (provided by applicant): The goal of this proposal is to better understand the role of the song control system in the perception of conspecific song in adult songbirds. Songbirds must not only learn to produce songs, but also learn to recognize conspecific individuals based on auditory communication. Previous research has established that lesions to areas within the song control system alter a bird's ability to make discriminations between familiar songs. Also, molecular techniques have been used to correlate auditory experience with protein phosphorylation within neurons of the song control system. The proposed experiments will investigate both the mechanisms and structures necessary for songbirds to process auditory information and form long term memories. Three hypotheses will be tested: (1) the phosphorylation of CREB is necessary in the formation of new auditory memories, (2) the anterior forebrain pathway is necessary for the recognition of familiar songs, and (3) the neostriatal nucleus HVc is necessary for the perception of conspecific song. I will test hypotheses (1) and (2) in wild song sparrows by simulating social interactions that the birds have when defending their territories during the breeding season. Hypothesis (3) will be tested with canaries in the laboratory using an operant conditioning task. These studies will increase our knowledge of the way in which songbirds perceive and learn to recognize the songs of conspecifics.

描述（由申请人提供）：本提案的目标是更好地理解鸣叫控制系统在成年鸣禽感知同种鸣叫中的作用。鸣禽不仅要学会唱歌，还要学会根据听觉交流来识别同一个体。先前的研究已经证实，鸣叫控制系统内区域的损伤会改变鸟类区分熟悉的鸣叫的能力。此外，分子技术已被用来将听觉体验与歌曲控制系统神经元内的蛋白质磷酸化相关联。拟议的实验将研究鸣禽处理听觉信息和形成长期记忆所需的机制和结构。将测试三个假设：（1）CREB ​​的磷酸化对于新听觉记忆的形成是必要的，（2）前脑通路对于识别熟悉的歌曲是必要的，（3）新纹状体核 HVc 对于识别熟悉的歌曲是必要的。对同种歌曲的感知。我将通过模拟鸟类在繁殖季节保卫领地时的社交互动，在野生鸣雀中检验假设（1）和（2）。假设（3）将在实验室中使用操作条件任务用金丝雀进行测试。这些研究将增加我们对鸣禽感知和学习识别同种歌曲的方式的了解。