ANTIPSYCHOTIC DRUGS: SCIENCE, PRACTICE, AND CULTURE

抗精神病药物：科学、实践和文化

基本信息

批准号：
6778229
负责人：
JOEL T BRASLOW
金额：
$ 16.77万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2000
资助国家：
美国
起止时间：
2000-08-01 至 2006-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6778229
关键词：
antipsychotic agents clinical research culture epidemiology history of life science human data medical records neuropsychology publications socioenvironment

项目摘要

The candidate is a psychiatrist-historian whose long-term career goal is to probe fundamental questions about how clinical practices-especially the care of the chronic mentally ill-are shaped by the clinical sciences and sociocultural factors. The candidate's immediate career goals are to become an independent researcher capable of employing a variety of health services research, statistical, and qualitative methods to answer questions of immediate policy, scientific, and clinical importance. Research career development plan: To accomplish these career goals, the applicant proposes a career development plan that involves: 1) course work in quality of care, statistics, qualitative methods, and the sociology of science; and 2) in- depth supervision in the quantitative and qualitative analysis of clinical practices and the clinical science of antipsychotic medications from 1954 to 1994. Description of research project: The research will examine patient records from a VA, state, and university based hospital, as well as treatment-outcome literature, psychiatric textbooks, psychiatric newsletters, and pharmaceutical industry publications. Melding qualitative and quantitative methods, the overall goal of the project is to understand the ways in which clinical science informs clinical decisions by way of a historical examination of antipsychotic drugs. The specific aims are: 1. Assess real world clinical practices in terms of a) patterns of antipsychotic drug use; and b) physicians' determinations of treatable psychiatric disease and effective outcome as shaped by cultural and scientific values and beliefs. 2. Assess clinical science in terms of a) its scientific evolution; b) its meaning to researchers; and c) its social and cultural values. Environment: The proposed training and research will take place at the UCLA Health Services Research Center, one of the country's leading centers for health services research. It also has close institutional and research affiliations with the Rand Corporation.

候选人是一名精神科医生，他的长期职业目标是探究有关临床实践的基本问题，尤其是对临床科学和社会文化因素造成的慢性精神疾病的照顾。候选人的直接职业目标是成为一名独立研究人员，能够采用各种健康服务研究，统计和定性方法来回答有关即时政策，科学和临床重要性问题的问题。研究职业发展计划：为了实现这些职业目标，申请人提出了一项职业发展计划，其中涉及：1）护理质量，统计，定性方法和科学社会学的课程；和2）对临床实践的定量和定性分析和抗精神病药的临床科学的深入监督。从1954年到1994年。研究项目的描述：研究将检查来自VA，州和大学医院的患者记录，以及基于VA的医院，以及治疗结果，治疗经验文献，精神病学教科书，精神病学新闻，精神病学新闻，和医学新闻，和制药术。融合定性和定量方法，该项目的总体目标是通过对抗精神病药的历史检查来了解临床科学对临床决策的信息。具体目的是：1。根据a）抗精神病药的模式评估现实世界的临床实践； b）医师对可治疗的精神疾病和有效结果的确定是由文化和科学价值观和信念所塑造的。 2。根据a）科学进化评估临床科学； b）对研究人员的意义； c）其社会和文化价值观。环境：拟议的培训和研究将在UCLA卫生服务研究中心（该国卫生服务研究中心之一）举行。它还与兰德公司（Rand Corporation）有着密切的机构和研究隶属关系。